Products
Human Fc gamma receptor IIB (FcγRIIB, CD32b, T232) His+Avi (Biotinylated) for antibody Fc&Fc
Receptor binding affinity assay (Competitive ELISA immunoassay, SRP assay or BLI assay)
Cat No.: GMP-BioFcR-ag-011
Human Fc gamma receptor IIB (FcγRIIB, CD32b, T232) His+Avi (Biotinylated) is used to measure the affinity of antibodies for it.
The Fc receptor binding assay (Competitive ELISA immunoassay, SRP assay or BLI assay) plays a vital role in the development of
therapeutic antibodies.
GeneMedi provides Human Fc gamma receptor IIB (FcγRIIB, CD32b, T232) His+Avi (Biotinylated)
The receptor has been classified based on its affinity for IgG1, IgG3, IgG4. The Fc receptor is expressed on many immune cells and binds to the specific immunoglobulin, then modulating the immune response.
Order information
GeneMedi provides two kinds of Human Fc gamma receptor IIB (FcγRIIB, CD32b, T232)(GMP-BioFcR-ag-011), GMP-BioFcR-ag-011-1 is with the tag His and Avi, GMP-BioFcR-ag-011-2 is Biotinylated and also with the tag His and Avi.
| Catalog No. | Description | Price (In USD) |
Qty (Quantity) | Sum(In USD) |
|---|---|---|---|---|
| GMP-BioFcR-ag-011-1 | Human Fc gamma receptor IIB (FcγRIIB, CD32b, T232) His+Avi Size:1mg | 5990 | ||
| GMP-BioFcR-ag-011-1 | Human Fc gamma receptor IIB (FcγRIIB, CD32b, T232) His+Avi Size:10mg | 38790 | ||
| GMP-BioFcR-ag-011-1 | Human Fc gamma receptor IIB (FcγRIIB, CD32b, T232) His+Avi Size:100mg | 258000 | ||
| GMP-BioFcR-ag-011-2 | Human Fc gamma receptor IIB (FcγRIIB, CD32b, T232) His+Avi, Biotinylated Size:1mg | 6990 | ||
| GMP-BioFcR-ag-011-2 | Human Fc gamma receptor IIB (FcγRIIB, CD32b, T232) His+Avi, Biotinylated Size:10mg | 43790 | ||
| GMP-BioFcR-ag-011-2 | Human Fc gamma receptor IIB (FcγRIIB, CD32b, T232) His+Avi, Biotinylated Size:100mg | 293000 | ||
| GMP-BioFcR-ag-011 | Size≥100mg | Inquiry | ||
| Shipping Cost: | 760.00 | |||
| Total: | ||||
Description
| Products Name | GMP-BioFcR-ag-011-1: Human Fc gamma receptor IIB (FcγRIIB, CD32b, T232) His+Avi GMP-BioFcR-ag-011-2: Human Fc gamma receptor IIB (FcγRIIB, CD32b, T232) His+Avi, Biotinylated |
| Products Description | Human Fc gamma receptor IIB (FcγRIIB, CD32b, T232) His+Avi (Biotinylated) is used to measure the affinity of antibodies for it. The Fc receptor binding assay (Competitive ELISA immunoassay, SRP assay or BLI assay) plays a vital role in the development of therapeutic antibodies. GeneMedi provides Human Fc gamma receptor IIB (FcγRIIB, CD32b, T232) His+Avi (Biotinylated). The receptor has been classified based on its affinity for IgG1, IgG2, IgG3, IgG4 . The Fc receptor is expressed on many immune cells and binds to the specific immunoglobulin, then modulating the immune response. |
| Isotype | Fc gamma receptor IIB (FcγRIIB, CD32b) |
| Receptor name | Fc gamma receptor IIB (FcγRIIB, CD32b, T232) |
| Species | Human |
| Principal antibody ligand | IgG1, IgG2, IgG3, IgG4 |
| Major role | Inhibition |
| Effect following binding to antibody | ADCC, ADCP |
| WT/Mutation | Mutation |
| Mutant variants functions vs WT | decreased inhibitory activity |
| Fc Modifications or Mutations (Reduced effector function) |
LE (ADCC),LALA(ADCC, ADCP,),LALA-PG (ADCP),TM,DA (ADCC, ADCP),GRLR (ADCC), IgG2/G4, IgG2m4 (ADCC, ADCP),Gly237Ala (ADCP),Glu318Ala (ADCP), Glu233Pro, IgG2σ (ADCC, ADCP), IgG1σ(ADCC) |
| Fc Modifications or Mutations (Enhanced effector function) |
IgG1/IgA2 (ADCC), GASDALIE (ADCC), DAE (ADCC, ADCP) |
| Application | Antibody Fc&Fc Receptor binding affinity assay (Competitive ELISA immunoassay, SRP assay or BLI assay) |
| Formulation | Supplied as a 0.2 μM filtered solution of PBS, PH7.4. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
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