Human Fc gamma receptor IIB (FcγRIIB, CD32b, T232) His+Avi (Biotinylated) for antibody Fc&Fc
Receptor binding affinity assay (Competitive ELISA immunoassay, SRP assay or BLI assay)  

Cat No.: GMP-BioFcR-ag-011

Human Fc gamma receptor IIB (FcγRIIB, CD32b, T232) His+Avi (Biotinylated) is used to measure the affinity of antibodies for it.

The Fc receptor binding assay (Competitive ELISA immunoassay, SRP assay or BLI assay) plays a vital role in the development of
therapeutic antibodies.

GeneMedi provides Human Fc gamma receptor IIB (FcγRIIB, CD32b, T232) His+Avi (Biotinylated)
The receptor has been classified based on its affinity for IgG1, IgG3, IgG4. The Fc receptor is expressed on many immune cells and binds to the specific immunoglobulin, then modulating the immune response.


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GeneMedi provides two kinds of Human Fc gamma receptor IIB (FcγRIIB, CD32b, T232)(GMP-BioFcR-ag-011), GMP-BioFcR-ag-011-1 is with the tag His and Avi, GMP-BioFcR-ag-011-2 is Biotinylated and also with the tag His and Avi.

Catalog No. Description Price
(In USD)		 Qty (Quantity) Sum(In USD)
GMP-BioFcR-ag-011-1 Human Fc gamma receptor IIB (FcγRIIB, CD32b, T232) His+Avi    Size:1mg 5990
GMP-BioFcR-ag-011-1 Human Fc gamma receptor IIB (FcγRIIB, CD32b, T232) His+Avi    Size:10mg 38790
GMP-BioFcR-ag-011-1 Human Fc gamma receptor IIB (FcγRIIB, CD32b, T232) His+Avi     Size:100mg 258000
GMP-BioFcR-ag-011-2 Human Fc gamma receptor IIB (FcγRIIB, CD32b, T232) His+Avi, Biotinylated    Size:1mg 6990
GMP-BioFcR-ag-011-2 Human Fc gamma receptor IIB (FcγRIIB, CD32b, T232) His+Avi, Biotinylated    Size:10mg 43790
GMP-BioFcR-ag-011-2 Human Fc gamma receptor IIB (FcγRIIB, CD32b, T232) His+Avi, Biotinylated    Size:100mg 293000
GMP-BioFcR-ag-011 Size≥100mg Inquiry
Shipping Cost: 760.00
Total:

For more than 100mg, click here for inquiry. >>


Description

Products Name GMP-BioFcR-ag-011-1: Human Fc gamma receptor IIB (FcγRIIB, CD32b, T232) His+Avi
GMP-BioFcR-ag-011-2: Human Fc gamma receptor IIB (FcγRIIB, CD32b, T232) His+Avi, Biotinylated
Products Description Human Fc gamma receptor IIB (FcγRIIB, CD32b, T232) His+Avi (Biotinylated) is used to measure the affinity of antibodies for it. The Fc receptor binding assay (Competitive ELISA immunoassay, SRP assay or BLI assay) plays a vital role in the development of therapeutic antibodies. GeneMedi provides Human Fc gamma receptor IIB (FcγRIIB, CD32b, T232) His+Avi (Biotinylated). The receptor has been classified based on its affinity for IgG1, IgG2, IgG3, IgG4 . The Fc receptor is expressed on many immune cells and binds to the specific immunoglobulin, then modulating the immune response.
Isotype Fc gamma receptor IIB (FcγRIIB, CD32b)
Receptor name Fc gamma receptor IIB (FcγRIIB, CD32b, T232)
Species Human
Principal antibody ligand IgG1, IgG2, IgG3, IgG4
Major role Inhibition
Effect following binding to antibody ADCC, ADCP
WT/Mutation Mutation
Mutant variants functions vs WT decreased inhibitory activity
Fc Modifications or Mutations 
(Reduced effector function) 		LE (ADCC),LALA(ADCC, ADCP,),LALA-PG (ADCP),TM,DA (ADCC, ADCP),GRLR (ADCC), IgG2/G4, IgG2m4 (ADCC, ADCP),Gly237Ala (ADCP),Glu318Ala (ADCP), Glu233Pro, IgG2σ (ADCC, ADCP), IgG1σ(ADCC)
Fc Modifications or Mutations 
(Enhanced effector function) 		IgG1/IgA2 (ADCC), GASDALIE (ADCC), DAE (ADCC, ADCP)
Application Antibody Fc&Fc Receptor binding affinity assay (Competitive ELISA immunoassay, SRP assay or BLI assay)  
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.