Human Fc gamma receptor I (FcγRI, CD64) His+Avi (Biotinylated) for antibody Fc&Fc 
Receptor binding affinity assay(Competitive ELISA immunoassay, SRP assay or BLI assay)  

Cat No.: GMP-BioFcR-ag-001

Human Fc gamma receptor I (FcγRI, CD64) His+Avi (Biotinylated) is used to measure the affinity of antibodies for it. 

The Fc receptor binding assay (Competitive ELISA immunoassay, SRP assay or BLI assay) plays a vital role in the development of 
therapeutic antibodies.

GeneMedi provides Human Fc gamma receptor I (FcγRI, CD64) His+Avi (Biotinylated). 
The receptor has been classified based on its affinity for IgG1, IgG3, IgG4. The Fc receptor is expressed on many immune cells and binds to the specific immunoglobulin, then modulating the immune response.


Order information



GeneMedi provides two kinds of Human Fc gamma receptor I (FcγRI, CD64) (GMP-BioFcR-ag-001), GMP-BioFcR-ag-001-1 is with the tag His and Avi, GMP-BioFcR-ag-001-2 is Biotinylated and also with the tag His and Avi.

Catalog No. Description Price
(In USD)		 Qty (Quantity) Sum(In USD)
GMP-BioFcR-ag-001-1 Human Fc gamma receptor I (FcγRI, CD64) His+Avi Size:1mg 5990
GMP-BioFcR-ag-001-1 Human Fc gamma receptor I (FcγRI, CD64) His+Avi Size:10mg 38790
GMP-BioFcR-ag-001-1 Human Fc gamma receptor I (FcγRI, CD64) His+Avi Size:100mg 258000
GMP-BioFcR-ag-001-2 Human Fc gamma receptor I (FcγRI, CD64) His+Avi, Biotinylated Size:1mg 6990
GMP-BioFcR-ag-001-2 Human Fc gamma receptor I (FcγRI, CD64) His+Avi, Biotinylated Size:10mg 43790
GMP-BioFcR-ag-001-2 Human Fc gamma receptor I (FcγRI, CD64) His+Avi, Biotinylated Size:100mg 293000
GMP-BioFcR-ag-001 Size≥100mg Inquiry
Shipping Cost: 760.00
Total:

For more than 100mg, click here for inquiry. >>


Description

Products Name GMP-BioFcR-ag-001-1: Human Fc gamma receptor I (FcγRI, CD64) His+Avi
GMP-BioFcR-ag-001-2: Human Fc gamma receptor I (FcγRI, CD64) His+Avi, Biotinylated
Products Description Human Fc gamma receptor I (FcγRI, CD64) His+Avi (Biotinylated) is used to measure the affinity of antibodies for it. The Fc receptor binding assay (Competitive ELISA immunoassay, SRP assay or BLI assay) plays a vital role in the development of therapeutic antibodies. GeneMedi provides Human Fc gamma receptor I (FcγRI, CD64) His+Avi (Biotinylated). The receptor has been classified based on its affinity for IgG1, IgG3, IgG4. The Fc receptor is expressed on many immune cells and binds to the specific immunoglobulin, then modulating the immune response.
Isotype Fc gamma receptor I (FcγRI, CD64)
Receptor nameFc gamma receptor I (FcγRI, CD64)
SpeciesHuman
Principal antibody ligandIgG1, IgG3, IgG4
Major roleActivation
Effect following binding to antibodyADCC, ADCP
WT/MutationWT
Mutant variants functions vs WTN/A
Fc Modifications or Mutations 
(Reduced effector function)		LE (ADCC),LALA(ADCC, ADCP,), LALA-PG(ADCP), TM, DA(ADCC, ADCP), GRLR(ADCC), IgG2/G4, IgG2m4(ADCC, ADCP), SPLE in IgG4, Glu233Pro, IgG2σ(ADCC, ADCP), IgG1σ(ADCC), Asn297Ala or Gly or Gln(ADCC, ADCP), IgG4 PAA(ADCC)
Fc Modifications or Mutations 
(Enhanced effector function)		IgG1/IgA2 (ADCC), DAE (ADCC, ADCP), IgGA (ADCC, ADCP), Multimeric IgG
Application Antibody Fc&Fc Receptor binding affinity assay (Competitive ELISA immunoassay, SRP assay or BLI assay)  
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.