Diagnostic anti-[prion] antibodies pairs for testing in ELISA, Lateral flow immunoassay (LFIA) and other immunoassays

The Prion and Public Health Office within DHCPP fulfills CDC's responsibilities as the lead agency for monitoring the occurrence of human prion diseases in the United States. The office coordinates CDC's activities and programs related to prion diseases as well as to select neurological diseases and syndromes of unknown etiology.

Prion diseases, or transmissible spongiform encephalopathies (TSEs), are a family of rare progressive neurodegenerative disorders that affect both humans and animals. They are distinguished by long incubation periods, characteristic spongiform changes associated with neuronal loss, and a failure to induce inflammatory response.

The causative agent of TSEs is believed to be a prion. A prion is an abnormal, transmissible agent that is able to induce abnormal folding of normal cellular prion proteins in the brain, leading to brain damage and the characteristics signs and symptoms of the disease. Prion diseases are usually rapidly progressive and always fatal.Genemedi produces core diagnostic ingredients-validated antibodies pairs Mouse anti-Prion monoclonal Antibody for rapid test kit of Ruan Toxin to evaluate the related human infectious disease.The paired antibodies are both monoclonal antibody(mab).

All the antibodies and antiges of animal disease test are suitable for in functional ELISA, and other immunoassays in diagnostics.The antibody can act as a capture antibody and detection antibody. Antigens are validated as positive control materials.

Order information

Catalog No.	Package	Price(In USD)	Qty (Quantity)	Sum(In USD)
GMP-prion-1Ab-1mg	1mg	1953
GMP-prion-1Ab-10mg	10mg	13671
GMP-prion-1Ab-100mg	100mg	95697
GMP-prion-1Ab-xmg	≥100mg	Inquiry
			Shipping Cost:	760.00
			Total:

Description

Antigen & Antibody Name	Mouse anti-Prion monoclonal Antibody
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Antibody Binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays in[Ruan Toxin)] level test in human infectious disease diagnositcs.
Tag	mFc
Products description	The Prion and Public Health Office within DHCPP fulfills CDC's responsibilities as the lead agency for monitoring the occurrence of human prion diseases in the United States. The office coordinates CDC's activities and programs related to prion diseases as well as to select neurological diseases and syndromes of unknown etiology. Prion diseases, or transmissible spongiform encephalopathies (TSEs), are a family of rare progressive neurodegenerative disorders that affect both humans and animals. They are distinguished by long incubation periods, characteristic spongiform changes associated with neuronal loss, and a failure to induce inflammatory response. The causative agent of TSEs is believed to be a prion. A prion is an abnormal, transmissible agent that is able to induce abnormal folding of normal cellular prion proteins in the brain, leading to brain damage and the characteristics signs and symptoms of the disease. Prion diseases are usually rapidly progressive and always fatal.
Purity	Purity: ≥95% (SDS-PAGE)
Application	ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA) and Immunonephelometry.
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.