The nucleocapsids of enveloped RNA viruses are fairly simple structures that contain only one major structural protein, often referred to as the nucleocapsid protein or core protein. This protein is usually quite basic or has a basic domain. It binds to the viral RNA and encapsidates it to form the nucleocapsid. For most RNA viruses, nucleocapsids can be recognized as distinct structures within the infected cell and can be isolated from virions by treatment with detergents that dissolve the envelope.
The nucleocapsids of alphaviruses, and probably flaviviruses and arteriviruses as well, are regular icosahedral structures, and there are no other proteins within the nucleocapsid other than the nucleocapsid protein. In contrast, the nucleocapsids of all minus-strand viruses are helical and contain, in addition to the major nucleocapsid protein, two or more minor proteins that possess enzymatic activity. As described, the nucleocapsids of minus-strand RNA viruses remain intact within the cell during the entire infection cycle and serve as machines that make viral RNA. The coronaviruses also have helical nucleocapsids, but being plus-strand RNA viruses they do not need to carry enzymes in the virion to initiate infection. The helical nucleocapsids of (-) RNA viruses appear disordered within the envelope of all viruses except the rhabdoviruses, in which they are coiled in a regular fashion (see later).
Genemedi produces core diagnostic ingredients for test of infectious disease and related syndrome.
GeneMedi offers paired diagnostics grade Nucleocapsid protein (Nucleocapsid) ) antibodies (monoclonal antibody, mab) and Nucleocapsid protein (Nucleocapsid) ) antigens for infectious disease rapid test kit of Nucleocapsid protein (Nucleocapsid) ) testing in ELISA test,Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT.
All the antibodies and antigens for infectious disease test are suitable for in functional ELISA, and other immunoassays in dignostics.The antibodies can act as a capture antibody and detection antibody.The antigens can be used for antibodies rapid test of infectious disease.
Order information
Description
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Cat No.
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GMP-Nucleocapsid-Ag |
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Product Name
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Nucleocapsid Antigen
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Expression platform
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E.coli
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| Isotypes | Recombinant Antigen
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| Bioactivity validation | Nucleocapsid protein (Nucleocapsid) Antibody Binding, lImmunogen in Sandwich ELISA test, Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT
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| Tag | His
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| Products description | Recombinant Nucleocapsid protein (Nucleocapsid, His Tag) is produced by E.coli expression system with a 6His tag.
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| Specics | NA
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| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA) and Immunonephelometry.
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| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
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Cat No.
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GMP-Nucleocapsid-Ab-1; GMP-Nucleocapsid-Ab-2 |
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Product Name
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Nucleocapsid Monoclonal Antibody
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Expression platform
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CHO |
| Isotypes | Mouse IgG |
| Bioactivity validation | Human Nucleocapsid protein (Nucleocapsid) protein binding, ELISA validated as capture antibody and detection antibody. Pair in Nucleocapsid level test and infectious disease evaluation.
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| Tag | mFc |
| Products description | Anti-Nucleocapsid protein (Nucleocapsid) mouse monoclonal antibody(mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody pair.
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| Specics | mouse |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA) and Immunonephelometry. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
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