Diagnostic recombinant Alpha-1-microglobulin (A1M) antigens (recombinant Alpha-1-microglobulin (A1M) ) protein) for kidney function (renal damages)A1M detection in positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA),immunonephelometry and POCT.

Urinary microproteins are becoming increasingly important in clinical diagnostics. They can contribute in the non-invasive early detection of renal abnormalities and the differentiation of various nephrological and urological pathologies.

Alpha-1-microglobulin (A1M, α1-microglobulin, sometimes also called Protein HC) is a microglobulin, a small globular protein. It is found in all vertebrates, including humans, and is distributed in blood plasma and extravascular tissues of all organs. It is synthesized in most cells of the body, but mainly in the liver from a gene that codes for the alpha-1-microglobulin/bikunin precursor. A1M can be used as an indicator of proteinuria. The test can be regarded as positive when the ratio of A1M (in milligrams) and creatinine in millimoles in the urine is over 0.7 mg/mmol.

A test for preeclampsia, where A1M serves as the diagnostic marker, has been proposed. It is based upon the fact that oxidative stress in the placenta tissue triggers the endogenous synthesis and plasma concentration of the protein.Alpha 1-microglobulin (A1M) is an immunomodulatory protein with a broad spectrum of possible clinical applications and seems a promising marker for evaluation of tubular function.

Genemedi produces core diagnostic ingredients for test of kidney function (renal damages) and related syndrome. GeneMedi offers paired diagnostics grade Alpha-1-microglobulin (A1M) antibodies (monoclonal antibody, mab) and Alpha-1-microglobulin (A1M) antigens for kidney function (renal damages) rapid test kit of Alpha-1-microglobulin (A1M) testing in positive control, ELISA test,Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT. All the antibodies and antigens for kidney function (renal damages) test are suitable for in functional ELISA, and other immunoassays in dignostics. The antibodies can act as a capture antibody and detection antibody. The antigens can be used for antibodies rapid test of kidney function (renal damages).

Order information

Catalog No.	Size	Price(In USD)	Qty (Quantity)	Sum(In USD)
GMP-A1M-Ag	Size:1mg	3090
GMP-A1M-Ag	Size:10mg	21890
GMP-A1M-Ag	Size:100mg	148000
GMP-A1M-Ag	≥100mg	Inquiry
			Shipping Cost:	760.00
			Total:

Description

Cat No.	GMP-A1M-Ag
Product Name	Recombinant Alpha-1-microglobulin (A1M, His Tag)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Alpha-1-microglobulin (A1M) Antibody Binding, Immunogen in Sandwich ELISA test, Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT
Tag	His
Products description	Recombinant Alpha-1-microglobulin (A1M, His Tag) is produced by E.coli expression system with a 6His tag.
Specics	NA
Purity	Purity: ≥95% (SDS-PAGE)
Application	positive control,ELISA test, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA) and Immunonephelometry.
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.