Recombinant multi-species TPO/ THPO/ MGDF protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine THPO protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: THPO, gene name: THPO, also named as MGDF, MKCSF, ML, MPLLG, THCYT1, TPO. Megakaryocytopoiesis is the cellular development process that leads to platelet production. The main functional protein encoded by this gene is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene. Mutations in this gene are the cause of thrombocythemia 1. Alternative promoter usage and differential splicing result in multiple transcript variants differing in the 5' UTR and/or coding region. Multiple AUG codons upstream of the main open reading frame (ORF) have been identified, and these upstream AUGs inhibit translation of the main ORF at different extent. [provided by RefSeq, Feb 2014].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-T99379-Ag-1Human THPO proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T99379-Ag-1Rat THPO proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T99379-Ag-1Mouse THPO proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T99379-Ag-1Cynomolgus/ Rhesus macaque THPO proteinCynomolgus/
Rhesus macaque		1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-T99379-Ag-1Feline THPO proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-T99379-Ag-1Canine THPO proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T99379-Ag-1Bovine THPO proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T99379-Ag-1Equine THPO proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00

For more than 100mg, click here forinquiry.>>


Description

Catalog No.GM-Tg-hg-T99379-Ag, GM-Tg-rg-T99379-Ag, GM-Tg-mg-T99379-Ag, GM-Tg-cynog-T99379-Ag,
GM-Tg-felg-T99379-Ag, GM-Tg-cang-T99379-Ag, GM-Tg-bovg-T99379-Ag, GM-Tg-equg-T99379-Ag-1
Products Name THPO protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NameTHPO
Protein Sub-locationSecreted Protein/Potential Cytokines
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine THPO protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.