Recombinant multi-species THB/ THRB/ C-ERBA-2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine THRB protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The target: THRB, gene name: THRB, also named as C-ERBA-2, C-ERBA-BETA, ERBA2, GRTH, NR1A2, PRTH, THR11, THRB2, THRB. The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Mutations in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH). Several alternatively spliced transcript variants encoding the same protein have been observed for this gene. [provided by RefSeq, Jul 2008].
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Catalog No. | Product Name | Species | Size | Price |
GM-Tg-hg-T98933-Ag-1 | Human THRB protein | Human | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-rg-T98933-Ag-1 | Rat THRB protein | Rat | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-mg-T98933-Ag-1 | Mouse THRB protein | Mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-cynog-T98933-Ag-1 | Cynomolgus/ Rhesus macaque THRB protein | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-felg-T98933-Ag-1 | Feline THRB protein | Feline | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-cang-T98933-Ag-1 | Canine THRB protein | Canine | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-bovg-T98933-Ag-1 | Bovine THRB protein | Bovine | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-bovg-T98933-Ag-1 | Equine THRB protein | Equine | 1mg/10mg/100mg/≥100mg | Inquiry |
Shipping Cost: | 760.00 |
Description
Catalog No. | GM-Tg-hg-T98933-Ag, GM-Tg-rg-T98933-Ag, GM-Tg-mg-T98933-Ag, GM-Tg-cynog-T98933-Ag, GM-Tg-felg-T98933-Ag, GM-Tg-cang-T98933-Ag, GM-Tg-bovg-T98933-Ag, GM-Tg-equg-T98933-Ag-1 |
Products Name | THRB protein |
Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
Target Name | THRB |
Protein Sub-location | Introcelluar Protein |
Isotypes | Recombinant protein |
Expression platform | Mammalian cell |
Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
Tag | His |
Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine THRB protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
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