Recombinant multi-species BAP1/ HUCEP-13/ UCHL2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Target products collectionGo to BAP1/BAP1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine BAP1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: BAP1, gene name: BAP1, also named as HUCEP-13, UCHL2, hucep-6. This gene belongs to the ubiquitin C-terminal hydrolase subfamily of deubiquitinating enzymes that are involved in the removal of ubiquitin from proteins. The encoded enzyme binds to the breast cancer type 1 susceptibility protein (BRCA1) via the RING finger domain of the latter and acts as a tumor suppressor. In addition, the enzyme may be involved in regulation of transcription, regulation of cell cycle and growth, response to DNA damage and chromatin dynamics. Germline mutations in this gene may be associated with tumor predisposition syndrome (TPDS), which involves increased risk of cancers including malignant mesothelioma, uveal melanoma and cutaneous melanoma. [provided by RefSeq, May 2013].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-T92628-Ag-1Human BAP1 proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T92628-Ag-1Rat BAP1 proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T92628-Ag-1Mouse BAP1 proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T92628-Ag-1Cynomolgus/ Rhesus macaque BAP1 proteinCynomolgus/
Rhesus macaque		1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-T92628-Ag-1Feline BAP1 proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-T92628-Ag-1Canine BAP1 proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T92628-Ag-1Bovine BAP1 proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T92628-Ag-1Equine BAP1 proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00

For more than 100mg, click here forinquiry.>>


Description

Catalog No.GM-Tg-hg-T92628-Ag, GM-Tg-rg-T92628-Ag, GM-Tg-mg-T92628-Ag, GM-Tg-cynog-T92628-Ag,
GM-Tg-felg-T92628-Ag, GM-Tg-cang-T92628-Ag, GM-Tg-bovg-T92628-Ag, GM-Tg-equg-T92628-Ag-1
Products Name BAP1 protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NameBAP1
Protein Sub-locationIntrocelluar Protein
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine BAP1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.