Recombinant multi-species I23O1/ IDO1/ IDO protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Target products collectionGo to IDO1/IDO1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IDO1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: IDO1, gene name: IDO1, also named as IDO, IDO-1, INDO. This gene encodes indoleamine 2,3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.[provided by RefSeq, Feb 2011].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-T89697-Ag-1Human IDO1 proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T89697-Ag-1Rat IDO1 proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T89697-Ag-1Mouse IDO1 proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T89697-Ag-1Cynomolgus/ Rhesus macaque IDO1 proteinCynomolgus/
Rhesus macaque		1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-T89697-Ag-1Feline IDO1 proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-T89697-Ag-1Canine IDO1 proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T89697-Ag-1Bovine IDO1 proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T89697-Ag-1Equine IDO1 proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00

For more than 100mg, click here forinquiry.>>


Description

Catalog No.GM-Tg-hg-T89697-Ag, GM-Tg-rg-T89697-Ag, GM-Tg-mg-T89697-Ag, GM-Tg-cynog-T89697-Ag,
GM-Tg-felg-T89697-Ag, GM-Tg-cang-T89697-Ag, GM-Tg-bovg-T89697-Ag, GM-Tg-equg-T89697-Ag-1
Products Name IDO1 protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NameIDO1
Protein Sub-locationIntrocelluar Protein
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IDO1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.