Recombinant multi-species E2AK3/ HsPEK/ EIF2AK3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Target products collectionGo to HsPEK/EIF2AK3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HsPEK/EIF2AK3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: HsPEK, gene name: EIF2AK3, also named as PEK, PERK, WRS. The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome. [provided by RefSeq, Sep 2015].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-T75015-Ag-1Human HsPEK/EIF2AK3 proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T75015-Ag-1Rat HsPEK/EIF2AK3 proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T75015-Ag-1Mouse HsPEK/EIF2AK3 proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T75015-Ag-1Cynomolgus/ Rhesus macaque HsPEK/EIF2AK3 proteinCynomolgus/
Rhesus macaque		1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-T75015-Ag-1Feline HsPEK/EIF2AK3 proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-T75015-Ag-1Canine HsPEK/EIF2AK3 proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T75015-Ag-1Bovine HsPEK/EIF2AK3 proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T75015-Ag-1Equine HsPEK/EIF2AK3 proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00

For more than 100mg, click here forinquiry.>>


Description

Catalog No.GM-Tg-hg-T75015-Ag, GM-Tg-rg-T75015-Ag, GM-Tg-mg-T75015-Ag, GM-Tg-cynog-T75015-Ag,
GM-Tg-felg-T75015-Ag, GM-Tg-cang-T75015-Ag, GM-Tg-bovg-T75015-Ag, GM-Tg-equg-T75015-Ag-1
Products Name HsPEK/EIF2AK3 protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NameHsPEK
Protein Sub-locationIntrocelluar Protein
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HsPEK/EIF2AK3 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.