Recombinant multi-species BMI1/ FLVI2/BMI1/ PCGF4 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine BMI1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The target: BMI1, gene name: BMI1, also named as FLVI2/BMI1, PCGF4, RNF51, flvi-2/bmi-1. This gene encodes a ring finger protein that is major component of the polycomb group complex 1 (PRC1). This complex functions through chromatin remodeling as an essential epigenetic repressor of multiple regulatory genes involved in embryonic development and self-renewal in somatic stem cells. This protein also plays a central role in DNA damage repair. This gene is an oncogene and aberrant expression is associated with numerous cancers and is associated with resistance to certain chemotherapies. A pseudogene of this gene is found on chromosome X. Read-through transcription also exists between this gene and the upstream COMM domain containing 3 (COMMD3) gene. [provided by RefSeq, Sep 2015].
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Catalog No. | Product Name | Species | Size | Price |
GM-Tg-hg-T74066-Ag-1 | Human BMI1 protein | Human | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-rg-T74066-Ag-1 | Rat BMI1 protein | Rat | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-mg-T74066-Ag-1 | Mouse BMI1 protein | Mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-cynog-T74066-Ag-1 | Cynomolgus/ Rhesus macaque BMI1 protein | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-felg-T74066-Ag-1 | Feline BMI1 protein | Feline | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-cang-T74066-Ag-1 | Canine BMI1 protein | Canine | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-bovg-T74066-Ag-1 | Bovine BMI1 protein | Bovine | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-bovg-T74066-Ag-1 | Equine BMI1 protein | Equine | 1mg/10mg/100mg/≥100mg | Inquiry |
Shipping Cost: | 760.00 |
Description
Catalog No. | GM-Tg-hg-T74066-Ag, GM-Tg-rg-T74066-Ag, GM-Tg-mg-T74066-Ag, GM-Tg-cynog-T74066-Ag, GM-Tg-felg-T74066-Ag, GM-Tg-cang-T74066-Ag, GM-Tg-bovg-T74066-Ag, GM-Tg-equg-T74066-Ag-1 |
Products Name | BMI1 protein |
Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
Target Name | BMI1 |
Protein Sub-location | Introcelluar Protein |
Isotypes | Recombinant protein |
Expression platform | Mammalian cell |
Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
Tag | His |
Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine BMI1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation | Supplied as a 0.2 μM filtered solution of PBS, PH7.4. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
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