Recombinant multi-species BMI1/ FLVI2/BMI1/ PCGF4 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine BMI1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: BMI1, gene name: BMI1, also named as FLVI2/BMI1, PCGF4, RNF51, flvi-2/bmi-1. This gene encodes a ring finger protein that is major component of the polycomb group complex 1 (PRC1). This complex functions through chromatin remodeling as an essential epigenetic repressor of multiple regulatory genes involved in embryonic development and self-renewal in somatic stem cells. This protein also plays a central role in DNA damage repair. This gene is an oncogene and aberrant expression is associated with numerous cancers and is associated with resistance to certain chemotherapies. A pseudogene of this gene is found on chromosome X. Read-through transcription also exists between this gene and the upstream COMM domain containing 3 (COMMD3) gene. [provided by RefSeq, Sep 2015].

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Catalog No.	Product Name	Species	Size	Price
GM-Tg-hg-T74066-Ag-1	Human BMI1 protein	Human	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-rg-T74066-Ag-1	Rat BMI1 protein	Rat	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-mg-T74066-Ag-1	Mouse BMI1 protein	Mouse	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cynog-T74066-Ag-1	Cynomolgus/ Rhesus macaque BMI1 protein	Cynomolgus/ Rhesus macaque	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-felg-T74066-Ag-1	Feline BMI1 protein	Feline	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cang-T74066-Ag-1	Canine BMI1 protein	Canine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T74066-Ag-1	Bovine BMI1 protein	Bovine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T74066-Ag-1	Equine BMI1 protein	Equine	1mg/10mg/100mg/≥100mg	Inquiry
Shipping Cost:				760.00

Description

Catalog No.	GM-Tg-hg-T74066-Ag, GM-Tg-rg-T74066-Ag, GM-Tg-mg-T74066-Ag, GM-Tg-cynog-T74066-Ag, GM-Tg-felg-T74066-Ag, GM-Tg-cang-T74066-Ag, GM-Tg-bovg-T74066-Ag, GM-Tg-equg-T74066-Ag-1
Products Name	BMI1 protein
Species	Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name	BMI1
Protein Sub-location	Introcelluar Protein
Isotypes	Recombinant protein
Expression platform	Mammalian cell
Bioactivity validation	Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag	His
Products description	Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine BMI1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity	Purity: ≥95% (SDS-PAGE)
Application	In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.