Recombinant multi-species ANGT/ AGT/ ANHU protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine AGT protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: AGT, gene name: AGT, also named as ANHU, SERPINA8, hFLT1. The protein encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure, body fluid and electrolyte homeostasis, and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease. [provided by RefSeq, Nov 2019].

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Catalog No.	Product Name	Species	Size	Price
GM-Tg-hg-T64485-Ag-1	Human AGT protein	Human	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-rg-T64485-Ag-1	Rat AGT protein	Rat	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-mg-T64485-Ag-1	Mouse AGT protein	Mouse	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cynog-T64485-Ag-1	Cynomolgus/ Rhesus macaque AGT protein	Cynomolgus/ Rhesus macaque	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-felg-T64485-Ag-1	Feline AGT protein	Feline	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cang-T64485-Ag-1	Canine AGT protein	Canine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T64485-Ag-1	Bovine AGT protein	Bovine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T64485-Ag-1	Equine AGT protein	Equine	1mg/10mg/100mg/≥100mg	Inquiry
Shipping Cost:				760.00

Description

Catalog No.	GM-Tg-hg-T64485-Ag, GM-Tg-rg-T64485-Ag, GM-Tg-mg-T64485-Ag, GM-Tg-cynog-T64485-Ag, GM-Tg-felg-T64485-Ag, GM-Tg-cang-T64485-Ag, GM-Tg-bovg-T64485-Ag, GM-Tg-equg-T64485-Ag-1
Products Name	AGT protein
Species	Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name	AGT
Protein Sub-location	Secreted Protein/Potential Cytokines
Isotypes	Recombinant protein
Expression platform	Mammalian cell
Bioactivity validation	Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag	His
Products description	Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine AGT protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity	Purity: ≥95% (SDS-PAGE)
Application	In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.