Recombinant multi-species RAD51/ BRCC5/ FANCR protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine RAD51 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: RAD51, gene name: RAD51, also named as BRCC5, FANCR, HRAD51, HsRad51, HsT16930, MRMV2A, RECA, RAD51. The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. This protein is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2009].

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Catalog No.	Product Name	Species	Size	Price
GM-Tg-hg-T63083-Ag-1	Human RAD51 protein	Human	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-rg-T63083-Ag-1	Rat RAD51 protein	Rat	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-mg-T63083-Ag-1	Mouse RAD51 protein	Mouse	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cynog-T63083-Ag-1	Cynomolgus/ Rhesus macaque RAD51 protein	Cynomolgus/ Rhesus macaque	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-felg-T63083-Ag-1	Feline RAD51 protein	Feline	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cang-T63083-Ag-1	Canine RAD51 protein	Canine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T63083-Ag-1	Bovine RAD51 protein	Bovine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T63083-Ag-1	Equine RAD51 protein	Equine	1mg/10mg/100mg/≥100mg	Inquiry
Shipping Cost:				760.00

Description

Catalog No.	GM-Tg-hg-T63083-Ag, GM-Tg-rg-T63083-Ag, GM-Tg-mg-T63083-Ag, GM-Tg-cynog-T63083-Ag, GM-Tg-felg-T63083-Ag, GM-Tg-cang-T63083-Ag, GM-Tg-bovg-T63083-Ag, GM-Tg-equg-T63083-Ag-1
Products Name	RAD51 protein
Species	Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name	RAD51
Protein Sub-location	Introcelluar Protein
Isotypes	Recombinant protein
Expression platform	Mammalian cell
Bioactivity validation	Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag	His
Products description	Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine RAD51 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity	Purity: ≥95% (SDS-PAGE)
Application	In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.