Recombinant multi-species CHK1/ CHEK1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CHK1/CHEK1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: CHK1, gene name: CHEK1, also named as CHK1. The protein encoded by this gene belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2011].

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Catalog No.	Product Name	Species	Size	Price
GM-Tg-hg-T62449-Ag-1	Human CHK1/CHEK1 protein	Human	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-rg-T62449-Ag-1	Rat CHK1/CHEK1 protein	Rat	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-mg-T62449-Ag-1	Mouse CHK1/CHEK1 protein	Mouse	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cynog-T62449-Ag-1	Cynomolgus/ Rhesus macaque CHK1/CHEK1 protein	Cynomolgus/ Rhesus macaque	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-felg-T62449-Ag-1	Feline CHK1/CHEK1 protein	Feline	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cang-T62449-Ag-1	Canine CHK1/CHEK1 protein	Canine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T62449-Ag-1	Bovine CHK1/CHEK1 protein	Bovine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T62449-Ag-1	Equine CHK1/CHEK1 protein	Equine	1mg/10mg/100mg/≥100mg	Inquiry
Shipping Cost:				760.00

Description

Catalog No.	GM-Tg-hg-T62449-Ag, GM-Tg-rg-T62449-Ag, GM-Tg-mg-T62449-Ag, GM-Tg-cynog-T62449-Ag, GM-Tg-felg-T62449-Ag, GM-Tg-cang-T62449-Ag, GM-Tg-bovg-T62449-Ag, GM-Tg-equg-T62449-Ag-1
Products Name	CHK1/CHEK1 protein
Species	Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name	CHK1
Protein Sub-location	Introcelluar Protein
Isotypes	Recombinant protein
Expression platform	Mammalian cell
Bioactivity validation	Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag	His
Products description	Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CHK1/CHEK1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity	Purity: ≥95% (SDS-PAGE)
Application	In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.