Recombinant multi-species CATB/ CTSB/ APPS protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CTSB protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The target: CTSB, gene name: CTSB, also named as APPS, CPSB, RECEUP. This gene encodes a member of the C1 family of peptidases. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate multiple protein products. These products include the cathepsin B light and heavy chains, which can dimerize to form the double chain form of the enzyme. This enzyme is a lysosomal cysteine protease with both endopeptidase and exopeptidase activity that may play a role in protein turnover. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer's disease, the most common cause of dementia. Overexpression of the encoded protein has been associated with esophageal adenocarcinoma and other tumors. Both Cathepsin B and Cathepsin L are involved in the cleavage of the spike protein from the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) upon its entry to the human host cell. Multiple pseudogenes of this gene have been identified. [provided by RefSeq, Sep 2020].
Order information
* GeneMedi provides NON-PROFIT PRICE to support Academic research.Please click inquiry for product quotation. → Inquiry
Catalog No. | Product Name | Species | Size | Price |
GM-Tg-hg-T61746-Ag-1 | Human CTSB protein | Human | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-rg-T61746-Ag-1 | Rat CTSB protein | Rat | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-mg-T61746-Ag-1 | Mouse CTSB protein | Mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-cynog-T61746-Ag-1 | Cynomolgus/ Rhesus macaque CTSB protein | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-felg-T61746-Ag-1 | Feline CTSB protein | Feline | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-cang-T61746-Ag-1 | Canine CTSB protein | Canine | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-bovg-T61746-Ag-1 | Bovine CTSB protein | Bovine | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-bovg-T61746-Ag-1 | Equine CTSB protein | Equine | 1mg/10mg/100mg/≥100mg | Inquiry |
Shipping Cost: | 760.00 |
Description
Catalog No. | GM-Tg-hg-T61746-Ag, GM-Tg-rg-T61746-Ag, GM-Tg-mg-T61746-Ag, GM-Tg-cynog-T61746-Ag, GM-Tg-felg-T61746-Ag, GM-Tg-cang-T61746-Ag, GM-Tg-bovg-T61746-Ag, GM-Tg-equg-T61746-Ag-1 |
Products Name | CTSB protein |
Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
Target Name | CTSB |
Protein Sub-location | Secreted Protein/Potential Cytokines |
Isotypes | Recombinant protein |
Expression platform | Mammalian cell |
Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
Tag | His |
Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CTSB protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation | Supplied as a 0.2 μM filtered solution of PBS, PH7.4. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
- GENEMEDI
- Email: [email protected] [email protected]
- Telephone: +86-21-50478399 Fax: 86-21-50478399
- Privacy Policy
- TECHNICAL SUPPORT
- Product FAQs
- Technical manuals
- Publications
- Email: [email protected]
![](/images/gototop.png)
![](https://www.genemedi.net/images/ad.png)