Recombinant multi-species ATF4/ ATF-4/ CREB-2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ATF-4/ATF4 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: ATF-4, gene name: ATF4, also named as CREB-2, CREB2, TAXREB67, TXREB. This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromosome at q28 in a region containing a large inverted duplication. [provided by RefSeq, Sep 2011].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-T53270-Ag-1Human ATF-4/ATF4 proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T53270-Ag-1Rat ATF-4/ATF4 proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T53270-Ag-1Mouse ATF-4/ATF4 proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T53270-Ag-1Cynomolgus/ Rhesus macaque ATF-4/ATF4 proteinCynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-T53270-Ag-1Feline ATF-4/ATF4 proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-T53270-Ag-1Canine ATF-4/ATF4 proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T53270-Ag-1Bovine ATF-4/ATF4 proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T53270-Ag-1Equine ATF-4/ATF4 proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00



Description

Catalog No.GM-Tg-hg-T53270-Ag, GM-Tg-rg-T53270-Ag, GM-Tg-mg-T53270-Ag, GM-Tg-cynog-T53270-Ag,
GM-Tg-felg-T53270-Ag, GM-Tg-cang-T53270-Ag, GM-Tg-bovg-T53270-Ag, GM-Tg-equg-T53270-Ag-1
Products Name ATF-4/ATF4 protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NameATF-4
Protein Sub-locationIntrocelluar Protein
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ATF-4/ATF4 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
FormulationSupplied as a 0.2 μM filtered solution of PBS, PH7.4.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.