Recombinant multi-species NQO1/ DHQU/ DIA4 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine NQO1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: NQO1, gene name: NQO1, also named as DHQU, DIA4, DTD, NMOR1, NMORI, QR1. This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].

Order information

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Catalog No.	Product Name	Species	Size	Price
GM-Tg-hg-T52389-Ag-1	Human NQO1 protein	Human	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-rg-T52389-Ag-1	Rat NQO1 protein	Rat	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-mg-T52389-Ag-1	Mouse NQO1 protein	Mouse	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cynog-T52389-Ag-1	Cynomolgus/ Rhesus macaque NQO1 protein	Cynomolgus/ Rhesus macaque	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-felg-T52389-Ag-1	Feline NQO1 protein	Feline	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cang-T52389-Ag-1	Canine NQO1 protein	Canine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T52389-Ag-1	Bovine NQO1 protein	Bovine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T52389-Ag-1	Equine NQO1 protein	Equine	1mg/10mg/100mg/≥100mg	Inquiry
Shipping Cost:				760.00

Description

Catalog No.	GM-Tg-hg-T52389-Ag, GM-Tg-rg-T52389-Ag, GM-Tg-mg-T52389-Ag, GM-Tg-cynog-T52389-Ag, GM-Tg-felg-T52389-Ag, GM-Tg-cang-T52389-Ag, GM-Tg-bovg-T52389-Ag, GM-Tg-equg-T52389-Ag-1
Products Name	NQO1 protein
Species	Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name	NQO1
Protein Sub-location	Introcelluar Protein
Isotypes	Recombinant protein
Expression platform	Mammalian cell
Bioactivity validation	Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag	His
Products description	Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine NQO1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity	Purity: ≥95% (SDS-PAGE)
Application	In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.