Recombinant multi-species TPA/ PLAT/ T-PA protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PLAT protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: PLAT, gene name: PLAT, also named as T-PA, TPA. This gene encodes tissue-type plasminogen activator, a secreted serine protease that converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. The encoded preproprotein is proteolytically processed by plasmin or trypsin to generate heavy and light chains. These chains associate via disulfide linkages to form the heterodimeric enzyme. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding, while decreased activity leads to hypofibrinolysis, which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016].

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Catalog No.	Product Name	Species	Size	Price
GM-Tg-hg-T45299-Ag-1	Human PLAT protein	Human	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-rg-T45299-Ag-1	Rat PLAT protein	Rat	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-mg-T45299-Ag-1	Mouse PLAT protein	Mouse	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cynog-T45299-Ag-1	Cynomolgus/ Rhesus macaque PLAT protein	Cynomolgus/ Rhesus macaque	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-felg-T45299-Ag-1	Feline PLAT protein	Feline	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cang-T45299-Ag-1	Canine PLAT protein	Canine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T45299-Ag-1	Bovine PLAT protein	Bovine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T45299-Ag-1	Equine PLAT protein	Equine	1mg/10mg/100mg/≥100mg	Inquiry
Shipping Cost:				760.00

Description

Catalog No.	GM-Tg-hg-T45299-Ag, GM-Tg-rg-T45299-Ag, GM-Tg-mg-T45299-Ag, GM-Tg-cynog-T45299-Ag, GM-Tg-felg-T45299-Ag, GM-Tg-cang-T45299-Ag, GM-Tg-bovg-T45299-Ag, GM-Tg-equg-T45299-Ag-1
Products Name	PLAT protein
Species	Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name	PLAT
Protein Sub-location	Secreted Protein/Potential Cytokines
Isotypes	Recombinant protein
Expression platform	Mammalian cell
Bioactivity validation	Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag	His
Products description	Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PLAT protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity	Purity: ≥95% (SDS-PAGE)
Application	In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.