Recombinant multi-species SH2B3/ IDDM20/ LNK protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SH2B3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: SH2B3, gene name: SH2B3, also named as IDDM20, LNK. This gene encodes a member of the SH2B adaptor family of proteins, which are involved in a range of signaling activities by growth factor and cytokine receptors. The encoded protein is a key negative regulator of cytokine signaling and plays a critical role in hematopoiesis. Mutations in this gene have been associated with susceptibility to celiac disease type 13 and susceptibility to insulin-dependent diabetes mellitus. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2014].

Order information

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Catalog No.	Product Name	Species	Size	Price
GM-Tg-hg-T44585-Ag-1	Human SH2B3 protein	Human	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-rg-T44585-Ag-1	Rat SH2B3 protein	Rat	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-mg-T44585-Ag-1	Mouse SH2B3 protein	Mouse	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cynog-T44585-Ag-1	Cynomolgus/ Rhesus macaque SH2B3 protein	Cynomolgus/ Rhesus macaque	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-felg-T44585-Ag-1	Feline SH2B3 protein	Feline	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cang-T44585-Ag-1	Canine SH2B3 protein	Canine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T44585-Ag-1	Bovine SH2B3 protein	Bovine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T44585-Ag-1	Equine SH2B3 protein	Equine	1mg/10mg/100mg/≥100mg	Inquiry
Shipping Cost:				760.00

Description

Catalog No.	GM-Tg-hg-T44585-Ag, GM-Tg-rg-T44585-Ag, GM-Tg-mg-T44585-Ag, GM-Tg-cynog-T44585-Ag, GM-Tg-felg-T44585-Ag, GM-Tg-cang-T44585-Ag, GM-Tg-bovg-T44585-Ag, GM-Tg-equg-T44585-Ag-1
Products Name	SH2B3 protein
Species	Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name	SH2B3
Protein Sub-location	Introcelluar Protein
Isotypes	Recombinant protein
Expression platform	Mammalian cell
Bioactivity validation	Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag	His
Products description	Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SH2B3 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity	Purity: ≥95% (SDS-PAGE)
Application	In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.