Recombinant multi-species CP46A/ CYP46A1/ CP46 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CYP46A1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: CYP46A1, gene name: CYP46A1, also named as CP46, CYP46. This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed in the brain, where it converts cholesterol to 24S-hydroxycholesterol. While cholesterol cannot pass the blood-brain barrier, 24S-hydroxycholesterol can be secreted in the brain into the circulation to be returned to the liver for catabolism. [provided by RefSeq, Jul 2008].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-T33641-Ag-1Human CYP46A1 proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T33641-Ag-1Rat CYP46A1 proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T33641-Ag-1Mouse CYP46A1 proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T33641-Ag-1Cynomolgus/ Rhesus macaque CYP46A1 proteinCynomolgus/
Rhesus macaque		1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-T33641-Ag-1Feline CYP46A1 proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-T33641-Ag-1Canine CYP46A1 proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T33641-Ag-1Bovine CYP46A1 proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T33641-Ag-1Equine CYP46A1 proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00

For more than 100mg, click here forinquiry.>>


Description

Catalog No.GM-Tg-hg-T33641-Ag, GM-Tg-rg-T33641-Ag, GM-Tg-mg-T33641-Ag, GM-Tg-cynog-T33641-Ag,
GM-Tg-felg-T33641-Ag, GM-Tg-cang-T33641-Ag, GM-Tg-bovg-T33641-Ag, GM-Tg-equg-T33641-Ag-1
Products Name CYP46A1 protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NameCYP46A1
Protein Sub-locationSecreted Protein/Potential Cytokines
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CYP46A1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.