Recombinant multi-species HNMT/ HMT-S1/ HNMT-S2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Target products collectionGo to HNMT/HNMT products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HNMT protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: HNMT, gene name: HNMT, also named as HMT-S1, HNMT-S2, MRT51, HNMT. In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene. [provided by RefSeq, Jul 2008].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-T17448-Ag-1Human HNMT proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T17448-Ag-1Rat HNMT proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T17448-Ag-1Mouse HNMT proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T17448-Ag-1Cynomolgus/ Rhesus macaque HNMT proteinCynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-T17448-Ag-1Feline HNMT proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-T17448-Ag-1Canine HNMT proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T17448-Ag-1Bovine HNMT proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T17448-Ag-1Equine HNMT proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00



Description

Catalog No.GM-Tg-hg-T17448-Ag, GM-Tg-rg-T17448-Ag, GM-Tg-mg-T17448-Ag, GM-Tg-cynog-T17448-Ag,
GM-Tg-felg-T17448-Ag, GM-Tg-cang-T17448-Ag, GM-Tg-bovg-T17448-Ag, GM-Tg-equg-T17448-Ag-1
Products Name HNMT protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NameHNMT
Protein Sub-locationIntrocelluar Protein
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HNMT protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
FormulationSupplied as a 0.2 μM filtered solution of PBS, PH7.4.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.