Recombinant multi-species TGFB2/ G-TSF/ LDS4 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TGFB2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: TGFB2, gene name: TGFB2, also named as G-TSF, LDS4, TGF-beta2. This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. Disruption of the TGF-beta/SMAD pathway has been implicated in a variety of human cancers. A chromosomal translocation that includes this gene is associated with Peters' anomaly, a congenital defect of the anterior chamber of the eye. Mutations in this gene may be associated with Loeys-Dietz syndrome. This gene encodes multiple isoforms that may undergo similar proteolytic processing. [provided by RefSeq, Aug 2016].

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Catalog No.	Product Name	Species	Size	Price
GM-Tg-hg-T14143-Ag-1	Human TGFB2 protein	Human	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-rg-T14143-Ag-1	Rat TGFB2 protein	Rat	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-mg-T14143-Ag-1	Mouse TGFB2 protein	Mouse	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cynog-T14143-Ag-1	Cynomolgus/ Rhesus macaque TGFB2 protein	Cynomolgus/ Rhesus macaque	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-felg-T14143-Ag-1	Feline TGFB2 protein	Feline	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cang-T14143-Ag-1	Canine TGFB2 protein	Canine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T14143-Ag-1	Bovine TGFB2 protein	Bovine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T14143-Ag-1	Equine TGFB2 protein	Equine	1mg/10mg/100mg/≥100mg	Inquiry
Shipping Cost:				760.00

Description

Catalog No.	GM-Tg-hg-T14143-Ag, GM-Tg-rg-T14143-Ag, GM-Tg-mg-T14143-Ag, GM-Tg-cynog-T14143-Ag, GM-Tg-felg-T14143-Ag, GM-Tg-cang-T14143-Ag, GM-Tg-bovg-T14143-Ag, GM-Tg-equg-T14143-Ag-1
Products Name	TGFB2 protein
Species	Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name	TGFB2
Protein Sub-location	Secreted Protein/Potential Cytokines
Isotypes	Recombinant protein
Expression platform	Mammalian cell
Bioactivity validation	Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag	His
Products description	Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TGFB2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity	Purity: ≥95% (SDS-PAGE)
Application	In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.