Recombinant multi-species DMD/ BMD/ CMD3B protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine DMD protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The target: DMD, gene name: DMD, also named as BMD, CMD3B, DXS142, DXS164, DXS206, DXS230, DXS239, DXS268, DXS269, DXS270, DXS272, MRX85. This gene spans a genomic range of greater than 2 Mb and encodes a large protein containing an N-terminal actin-binding domain and multiple spectrin repeats. The encoded protein forms a component of the dystrophin-glycoprotein complex (DGC), which bridges the inner cytoskeleton and the extracellular matrix. Deletions, duplications, and point mutations at this gene locus may cause Duchenne muscular dystrophy (DMD), Becker muscular dystrophy (BMD), or cardiomyopathy. Alternative promoter usage and alternative splicing result in numerous distinct transcript variants and protein isoforms for this gene. [provided by RefSeq, Dec 2016].
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Catalog No. | Product Name | Species | Size | Price |
GM-Tg-hg-T12909-Ag-1 | Human DMD protein | Human | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-rg-T12909-Ag-1 | Rat DMD protein | Rat | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-mg-T12909-Ag-1 | Mouse DMD protein | Mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-cynog-T12909-Ag-1 | Cynomolgus/ Rhesus macaque DMD protein | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-felg-T12909-Ag-1 | Feline DMD protein | Feline | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-cang-T12909-Ag-1 | Canine DMD protein | Canine | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-bovg-T12909-Ag-1 | Bovine DMD protein | Bovine | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-bovg-T12909-Ag-1 | Equine DMD protein | Equine | 1mg/10mg/100mg/≥100mg | Inquiry |
Shipping Cost: | 760.00 |
Description
Catalog No. | GM-Tg-hg-T12909-Ag, GM-Tg-rg-T12909-Ag, GM-Tg-mg-T12909-Ag, GM-Tg-cynog-T12909-Ag, GM-Tg-felg-T12909-Ag, GM-Tg-cang-T12909-Ag, GM-Tg-bovg-T12909-Ag, GM-Tg-equg-T12909-Ag-1 |
Products Name | DMD protein |
Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
Target Name | DMD |
Protein Sub-location | Introcelluar Protein |
Isotypes | Recombinant protein |
Expression platform | Mammalian cell |
Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
Tag | His |
Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine DMD protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
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