Recombinant multi-species PDE5A/ CGB-PDE/ CN5A protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Target products collectionGo to PDE5A/PDE5A products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PDE5A protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: PDE5A, gene name: PDE5A, also named as CGB-PDE, CN5A, PDE5. This gene encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5'-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-T07663-Ag-1Human PDE5A proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T07663-Ag-1Rat PDE5A proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T07663-Ag-1Mouse PDE5A proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T07663-Ag-1Cynomolgus/ Rhesus macaque PDE5A proteinCynomolgus/
Rhesus macaque		1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-T07663-Ag-1Feline PDE5A proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-T07663-Ag-1Canine PDE5A proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T07663-Ag-1Bovine PDE5A proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T07663-Ag-1Equine PDE5A proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00

For more than 100mg, click here forinquiry.>>


Description

Catalog No.GM-Tg-hg-T07663-Ag, GM-Tg-rg-T07663-Ag, GM-Tg-mg-T07663-Ag, GM-Tg-cynog-T07663-Ag,
GM-Tg-felg-T07663-Ag, GM-Tg-cang-T07663-Ag, GM-Tg-bovg-T07663-Ag, GM-Tg-equg-T07663-Ag-1
Products Name PDE5A protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NamePDE5A
Protein Sub-locationIntrocelluar Protein
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PDE5A protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.