Recombinant multi-species SOCS1/ CIS1/ CISH1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SOCS1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: SOCS1, gene name: SOCS1, also named as CIS1, CISH1, JAB, SOCS-1, SSI-1, SSI1, TIP-3, TIP3. This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival. [provided by RefSeq, Jul 2008].

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Catalog No.	Product Name	Species	Size	Price
GM-Tg-hg-T06800-Ag-1	Human SOCS1 protein	Human	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-rg-T06800-Ag-1	Rat SOCS1 protein	Rat	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-mg-T06800-Ag-1	Mouse SOCS1 protein	Mouse	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cynog-T06800-Ag-1	Cynomolgus/ Rhesus macaque SOCS1 protein	Cynomolgus/ Rhesus macaque	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-felg-T06800-Ag-1	Feline SOCS1 protein	Feline	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cang-T06800-Ag-1	Canine SOCS1 protein	Canine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T06800-Ag-1	Bovine SOCS1 protein	Bovine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T06800-Ag-1	Equine SOCS1 protein	Equine	1mg/10mg/100mg/≥100mg	Inquiry
Shipping Cost:				760.00

Description

Catalog No.	GM-Tg-hg-T06800-Ag, GM-Tg-rg-T06800-Ag, GM-Tg-mg-T06800-Ag, GM-Tg-cynog-T06800-Ag, GM-Tg-felg-T06800-Ag, GM-Tg-cang-T06800-Ag, GM-Tg-bovg-T06800-Ag, GM-Tg-equg-T06800-Ag-1
Products Name	SOCS1 protein
Species	Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name	SOCS1
Protein Sub-location	Introcelluar Protein
Isotypes	Recombinant protein
Expression platform	Mammalian cell
Bioactivity validation	Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag	His
Products description	Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SOCS1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity	Purity: ≥95% (SDS-PAGE)
Application	In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.