Recombinant multi-species SEBP2/ SECISBP2/ SBP2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SECISBP2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: SECISBP2, gene name: SECISBP2, also named as SBP2. The protein encoded by this gene is one of the essential components of the machinery involved in co-translational insertion of selenocysteine (Sec) into selenoproteins. Sec is encoded by the UGA codon, which normally signals translation termination. The recoding of UGA as Sec codon requires a Sec insertion sequence (SECIS) element; present in the 3' untranslated regions of eukaryotic selenoprotein mRNAs. This protein specifically binds to the SECIS element, which is stimulated by a Sec-specific translation elongation factor. Mutations in this gene have been associated with reduction in enzymatic activity of type II iodothyronine deiodinase (a selenoprotein) and abnormal thyroid hormone metabolism. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2017].

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Catalog No.	Product Name	Species	Size	Price
GM-Tg-hg-SE1640-Ag-1	Human SECISBP2 protein	Human	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-rg-SE1640-Ag-1	Rat SECISBP2 protein	Rat	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-mg-SE1640-Ag-1	Mouse SECISBP2 protein	Mouse	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cynog-SE1640-Ag-1	Cynomolgus/ Rhesus macaque SECISBP2 protein	Cynomolgus/ Rhesus macaque	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-felg-SE1640-Ag-1	Feline SECISBP2 protein	Feline	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cang-SE1640-Ag-1	Canine SECISBP2 protein	Canine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-SE1640-Ag-1	Bovine SECISBP2 protein	Bovine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-SE1640-Ag-1	Equine SECISBP2 protein	Equine	1mg/10mg/100mg/≥100mg	Inquiry
Shipping Cost:				760.00

Description

Catalog No.	GM-Tg-hg-SE1640-Ag, GM-Tg-rg-SE1640-Ag, GM-Tg-mg-SE1640-Ag, GM-Tg-cynog-SE1640-Ag, GM-Tg-felg-SE1640-Ag, GM-Tg-cang-SE1640-Ag, GM-Tg-bovg-SE1640-Ag, GM-Tg-equg-SE1640-Ag-1
Products Name	SECISBP2 protein
Species	Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name	SECISBP2
Protein Sub-location	Secreted Protein/Potential Cytokines
Isotypes	Recombinant protein
Expression platform	Mammalian cell
Bioactivity validation	Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag	His
Products description	Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SECISBP2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity	Purity: ≥95% (SDS-PAGE)
Application	In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.