Recombinant multi-species TRYB2/ TPSB2/ TPS2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TPSB2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The target: TPSB2, gene name: TPSB2, also named as TPS2, tryptaseB, tryptaseC. Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. These genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. The alleles of this gene exhibit an unusual amount of sequence variation, such that the alleles were once thought to represent two separate genes, beta II and beta III. Beta tryptases appear to be the main isoenzymes expressed in mast cells, whereas in basophils, alpha-tryptases predominate. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders. [provided by RefSeq, Jul 2008].
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Catalog No. | Product Name | Species | Size | Price |
GM-Tg-hg-SE1347-Ag-1 | Human TPSB2 protein | Human | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-rg-SE1347-Ag-1 | Rat TPSB2 protein | Rat | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-mg-SE1347-Ag-1 | Mouse TPSB2 protein | Mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-cynog-SE1347-Ag-1 | Cynomolgus/ Rhesus macaque TPSB2 protein | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-felg-SE1347-Ag-1 | Feline TPSB2 protein | Feline | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-cang-SE1347-Ag-1 | Canine TPSB2 protein | Canine | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-bovg-SE1347-Ag-1 | Bovine TPSB2 protein | Bovine | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-bovg-SE1347-Ag-1 | Equine TPSB2 protein | Equine | 1mg/10mg/100mg/≥100mg | Inquiry |
Shipping Cost: | 760.00 |
Description
Catalog No. | GM-Tg-hg-SE1347-Ag, GM-Tg-rg-SE1347-Ag, GM-Tg-mg-SE1347-Ag, GM-Tg-cynog-SE1347-Ag, GM-Tg-felg-SE1347-Ag, GM-Tg-cang-SE1347-Ag, GM-Tg-bovg-SE1347-Ag, GM-Tg-equg-SE1347-Ag-1 |
Products Name | TPSB2 protein |
Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
Target Name | TPSB2 |
Protein Sub-location | Secreted Protein/Potential Cytokines |
Isotypes | Recombinant protein |
Expression platform | Mammalian cell |
Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
Tag | His |
Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TPSB2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation | Supplied as a 0.2 μM filtered solution of PBS, PH7.4. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
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