Recombinant multi-species TIMP2/ CSC-21K/ DDC8 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TIMP2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: TIMP2, gene name: TIMP2, also named as CSC-21K, DDC8. This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix. [provided by RefSeq, Jul 2008].

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Catalog No.	Product Name	Species	Size	Price
GM-Tg-hg-SE1338-Ag-1	Human TIMP2 protein	Human	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-rg-SE1338-Ag-1	Rat TIMP2 protein	Rat	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-mg-SE1338-Ag-1	Mouse TIMP2 protein	Mouse	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cynog-SE1338-Ag-1	Cynomolgus/ Rhesus macaque TIMP2 protein	Cynomolgus/ Rhesus macaque	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-felg-SE1338-Ag-1	Feline TIMP2 protein	Feline	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cang-SE1338-Ag-1	Canine TIMP2 protein	Canine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-SE1338-Ag-1	Bovine TIMP2 protein	Bovine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-SE1338-Ag-1	Equine TIMP2 protein	Equine	1mg/10mg/100mg/≥100mg	Inquiry
Shipping Cost:				760.00

Description

Catalog No.	GM-Tg-hg-SE1338-Ag, GM-Tg-rg-SE1338-Ag, GM-Tg-mg-SE1338-Ag, GM-Tg-cynog-SE1338-Ag, GM-Tg-felg-SE1338-Ag, GM-Tg-cang-SE1338-Ag, GM-Tg-bovg-SE1338-Ag, GM-Tg-equg-SE1338-Ag-1
Products Name	TIMP2 protein
Species	Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name	TIMP2
Protein Sub-location	Secreted Protein/Potential Cytokines
Isotypes	Recombinant protein
Expression platform	Mammalian cell
Bioactivity validation	Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag	His
Products description	Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TIMP2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity	Purity: ≥95% (SDS-PAGE)
Application	In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.