Recombinant multi-species I18BP/ IL18BP/ IL18BPa protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IL18BP protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: IL18BP, gene name: IL18BP, also named as IL18BPa. The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011].

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Catalog No.	Product Name	Species	Size	Price
GM-Tg-hg-SE1023-Ag-1	Human IL18BP protein	Human	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-rg-SE1023-Ag-1	Rat IL18BP protein	Rat	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-mg-SE1023-Ag-1	Mouse IL18BP protein	Mouse	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cynog-SE1023-Ag-1	Cynomolgus/ Rhesus macaque IL18BP protein	Cynomolgus/ Rhesus macaque	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-felg-SE1023-Ag-1	Feline IL18BP protein	Feline	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cang-SE1023-Ag-1	Canine IL18BP protein	Canine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-SE1023-Ag-1	Bovine IL18BP protein	Bovine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-SE1023-Ag-1	Equine IL18BP protein	Equine	1mg/10mg/100mg/≥100mg	Inquiry
Shipping Cost:				760.00

Description

Catalog No.	GM-Tg-hg-SE1023-Ag, GM-Tg-rg-SE1023-Ag, GM-Tg-mg-SE1023-Ag, GM-Tg-cynog-SE1023-Ag, GM-Tg-felg-SE1023-Ag, GM-Tg-cang-SE1023-Ag, GM-Tg-bovg-SE1023-Ag, GM-Tg-equg-SE1023-Ag-1
Products Name	IL18BP protein
Species	Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name	IL18BP
Protein Sub-location	Secreted Protein/Potential Cytokines
Isotypes	Recombinant protein
Expression platform	Mammalian cell
Bioactivity validation	Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag	His
Products description	Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IL18BP protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity	Purity: ≥95% (SDS-PAGE)
Application	In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.