Recombinant multi-species GDF7/ BMP12 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Target products collectionGo to GDF7/GDF7 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GDF7 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: GDF7, gene name: GDF7, also named as BMP12. This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein may play a role in the differentiation of tendon cells and spinal cord interneurons. A mutation in this gene may be associated with increased risk for Barrett's esophagus and esophageal adenocarcinoma. [provided by RefSeq, Sep 2016].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-SE0942-Ag-1Human GDF7 proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-SE0942-Ag-1Rat GDF7 proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-SE0942-Ag-1Mouse GDF7 proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-SE0942-Ag-1Cynomolgus/ Rhesus macaque GDF7 proteinCynomolgus/
Rhesus macaque		1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-SE0942-Ag-1Feline GDF7 proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-SE0942-Ag-1Canine GDF7 proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-SE0942-Ag-1Bovine GDF7 proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-SE0942-Ag-1Equine GDF7 proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00

For more than 100mg, click here forinquiry.>>


Description

Catalog No.GM-Tg-hg-SE0942-Ag, GM-Tg-rg-SE0942-Ag, GM-Tg-mg-SE0942-Ag, GM-Tg-cynog-SE0942-Ag,
GM-Tg-felg-SE0942-Ag, GM-Tg-cang-SE0942-Ag, GM-Tg-bovg-SE0942-Ag, GM-Tg-equg-SE0942-Ag-1
Products Name GDF7 protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NameGDF7
Protein Sub-locationSecreted Protein/Potential Cytokines
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GDF7 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.