Recombinant multi-species ASIP/ AGSW/ AGTI protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Target products collectionGo to ASIP/ASIP products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ASIP protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: ASIP, gene name: ASIP, also named as AGSW, AGTI, AGTIL, ASP, SHEP9. In mice, the agouti gene encodes a paracrine signaling molecule that causes hair follicle melanocytes to synthesize pheomelanin, a yellow pigment, instead of the black or brown pigment, eumelanin. Pleiotropic effects of constitutive expression of the mouse gene include adult-onset obesity, increased tumor susceptibility, and premature infertility. This gene is highly similar to the mouse gene and encodes a secreted protein that may (1) affect the quality of hair pigmentation, (2) act as a pharmacological antagonist of alpha-melanocyte-stimulating hormone, (3) play a role in neuroendocrine aspects of melanocortin action, and (4) have a functional role in regulating lipid metabolism in adipocytes. [provided by RefSeq, Jul 2008].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-SE0681-Ag-1Human ASIP proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-SE0681-Ag-1Rat ASIP proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-SE0681-Ag-1Mouse ASIP proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-SE0681-Ag-1Cynomolgus/ Rhesus macaque ASIP proteinCynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-SE0681-Ag-1Feline ASIP proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-SE0681-Ag-1Canine ASIP proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-SE0681-Ag-1Bovine ASIP proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-SE0681-Ag-1Equine ASIP proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00



Description

Catalog No.GM-Tg-hg-SE0681-Ag, GM-Tg-rg-SE0681-Ag, GM-Tg-mg-SE0681-Ag, GM-Tg-cynog-SE0681-Ag,
GM-Tg-felg-SE0681-Ag, GM-Tg-cang-SE0681-Ag, GM-Tg-bovg-SE0681-Ag, GM-Tg-equg-SE0681-Ag-1
Products Name ASIP protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NameASIP
Protein Sub-locationSecreted Protein/Potential Cytokines
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ASIP protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.