Recombinant multi-species A2ML1/ CPAMD9/ OMS protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine A2ML1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: A2ML1, gene name: A2ML1, also named as CPAMD9, OMS, p170. This gene encodes a member of the alpha-macroglobulin superfamily. The encoded protein is thought to be an N-glycosylated monomeric protein that acts as an inhibitor of several proteases. It has been shown to form covalent interactions with proteases, and has been reported as the p170 antigen recognized by autoantibodies in the autoimmune disease paraneoplastic pemphigus (PNP; PMID:20805888). Mutations in these gene have also been associated with some cases of Noonan syndrome (NS; PMID:24939586) as well as some cases of otitis media (PMID:26121085). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2015].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-SE0631-Ag-1Human A2ML1 proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-SE0631-Ag-1Rat A2ML1 proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-SE0631-Ag-1Mouse A2ML1 proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-SE0631-Ag-1Cynomolgus/ Rhesus macaque A2ML1 proteinCynomolgus/
Rhesus macaque		1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-SE0631-Ag-1Feline A2ML1 proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-SE0631-Ag-1Canine A2ML1 proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-SE0631-Ag-1Bovine A2ML1 proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-SE0631-Ag-1Equine A2ML1 proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00

For more than 100mg, click here forinquiry.>>


Description

Catalog No.GM-Tg-hg-SE0631-Ag, GM-Tg-rg-SE0631-Ag, GM-Tg-mg-SE0631-Ag, GM-Tg-cynog-SE0631-Ag,
GM-Tg-felg-SE0631-Ag, GM-Tg-cang-SE0631-Ag, GM-Tg-bovg-SE0631-Ag, GM-Tg-equg-SE0631-Ag-1
Products Name A2ML1 protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NameA2ML1
Protein Sub-locationSecreted Protein/Potential Cytokines
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine A2ML1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.