Recombinant multi-species PLOD2/ BRKS2/ LH2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PLOD2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The target: PLOD2, gene name: PLOD2, also named as BRKS2, LH2, TLH. The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. Mutations in the coding region of this gene are associated with Bruck syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
Order information
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Catalog No. | Product Name | Species | Size | Price |
GM-Tg-hg-SE0415-Ag-1 | Human PLOD2 protein | Human | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-rg-SE0415-Ag-1 | Rat PLOD2 protein | Rat | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-mg-SE0415-Ag-1 | Mouse PLOD2 protein | Mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-cynog-SE0415-Ag-1 | Cynomolgus/ Rhesus macaque PLOD2 protein | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-felg-SE0415-Ag-1 | Feline PLOD2 protein | Feline | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-cang-SE0415-Ag-1 | Canine PLOD2 protein | Canine | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-bovg-SE0415-Ag-1 | Bovine PLOD2 protein | Bovine | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-bovg-SE0415-Ag-1 | Equine PLOD2 protein | Equine | 1mg/10mg/100mg/≥100mg | Inquiry |
Shipping Cost: | 760.00 |
Description
Catalog No. | GM-Tg-hg-SE0415-Ag, GM-Tg-rg-SE0415-Ag, GM-Tg-mg-SE0415-Ag, GM-Tg-cynog-SE0415-Ag, GM-Tg-felg-SE0415-Ag, GM-Tg-cang-SE0415-Ag, GM-Tg-bovg-SE0415-Ag, GM-Tg-equg-SE0415-Ag-1 |
Products Name | PLOD2 protein |
Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
Target Name | PLOD2 |
Protein Sub-location | Secreted Protein/Potential Cytokines |
Isotypes | Recombinant protein |
Expression platform | Mammalian cell |
Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
Tag | His |
Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PLOD2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation | Supplied as a 0.2 μM filtered solution of PBS, PH7.4. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
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