Recombinant multi-species GSH1/ GCLC/ GCL protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Target products collectionGo to GCLC/GCLC products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GCLC protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: GCLC, gene name: GCLC, also named as GCL, GCS, GLCL, GLCLC. Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction.[provided by RefSeq, Oct 2010].

Order information


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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-IP0890-Ag-1Human GCLC proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-IP0890-Ag-1Rat GCLC proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-IP0890-Ag-1Mouse GCLC proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-IP0890-Ag-1Cynomolgus/ Rhesus macaque GCLC proteinCynomolgus/
Rhesus macaque		1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-IP0890-Ag-1Feline GCLC proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-IP0890-Ag-1Canine GCLC proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-IP0890-Ag-1Bovine GCLC proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-IP0890-Ag-1Equine GCLC proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00

For more than 100mg, click here forinquiry.>>


Description

Catalog No.GM-Tg-hg-IP0890-Ag, GM-Tg-rg-IP0890-Ag, GM-Tg-mg-IP0890-Ag, GM-Tg-cynog-IP0890-Ag,
GM-Tg-felg-IP0890-Ag, GM-Tg-cang-IP0890-Ag, GM-Tg-bovg-IP0890-Ag, GM-Tg-equg-IP0890-Ag-1
Products Name GCLC protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NameGCLC
Protein Sub-locationIntrocelluar Protein
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GCLC protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.