Recombinant multi-species IDHP/ IDH2/ D2HGA2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Target products collectionGo to IDH2/IDH2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IDH2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: IDH2, gene name: IDH2, also named as D2HGA2, ICD-M, IDH, IDHM, IDP, IDPM, mNADP-IDH. Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-IP0248-Ag-1Human IDH2 proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-IP0248-Ag-1Rat IDH2 proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-IP0248-Ag-1Mouse IDH2 proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-IP0248-Ag-1Cynomolgus/ Rhesus macaque IDH2 proteinCynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-IP0248-Ag-1Feline IDH2 proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-IP0248-Ag-1Canine IDH2 proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-IP0248-Ag-1Bovine IDH2 proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-IP0248-Ag-1Equine IDH2 proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00



Description

Catalog No.GM-Tg-hg-IP0248-Ag, GM-Tg-rg-IP0248-Ag, GM-Tg-mg-IP0248-Ag, GM-Tg-cynog-IP0248-Ag,
GM-Tg-felg-IP0248-Ag, GM-Tg-cang-IP0248-Ag, GM-Tg-bovg-IP0248-Ag, GM-Tg-equg-IP0248-Ag-1
Products Name IDH2 protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NameIDH2
Protein Sub-locationIntrocelluar Protein
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IDH2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.