Recombinant multi-species PDE3A/ CGI-PDE/ CGI-PDE A protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PDE3A protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: PDE3A, gene name: PDE3A, also named as CGI-PDE, CGI-PDE A, CGI-PDE-A, HTNB. This gene encodes a member of the cGMP-inhibited cyclic nucleotide phosphodiesterase (cGI-PDE) family. cGI-PDE enzymes hydrolyze both cAMP and cGMP, and play critical roles in many cellular processes by regulating the amplitude and duration of intracellular cyclic nucleotide signals. The encoded protein mediates platelet aggregation and also plays important roles in cardiovascular function by regulating vascular smooth muscle contraction and relaxation. Inhibitors of the encoded protein may be effective in treating congestive heart failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-IP0012-Ag-1Human PDE3A proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-IP0012-Ag-1Rat PDE3A proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-IP0012-Ag-1Mouse PDE3A proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-IP0012-Ag-1Cynomolgus/ Rhesus macaque PDE3A proteinCynomolgus/
Rhesus macaque		1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-IP0012-Ag-1Feline PDE3A proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-IP0012-Ag-1Canine PDE3A proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-IP0012-Ag-1Bovine PDE3A proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-IP0012-Ag-1Equine PDE3A proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00

For more than 100mg, click here forinquiry.>>


Description

Catalog No.GM-Tg-hg-IP0012-Ag, GM-Tg-rg-IP0012-Ag, GM-Tg-mg-IP0012-Ag, GM-Tg-cynog-IP0012-Ag,
GM-Tg-felg-IP0012-Ag, GM-Tg-cang-IP0012-Ag, GM-Tg-bovg-IP0012-Ag, GM-Tg-equg-IP0012-Ag-1
Products Name PDE3A protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NamePDE3A
Protein Sub-locationIntrocelluar Protein
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PDE3A protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.