Pre-made Raxibacumab benchmark antibody (Whole mAb, anti-anthrax protective antigen (PA) [Bacillus anthracis] therapeutic antibody) for drug discovery and mechanism of action (MOA) research

Anti-anthrax protective antigen (PA) [Bacillus anthracis] therapeutic antibody (Pre-made Raxibacumab biosimilar, Whole mAb) is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Raxibacumab [1] is a human monoclonal antibody intended for the prophylaxis and treatment of inhaled anthrax. Its efficacy has been proven in rabbits and monkeys.[2] In December 212 raxibacumab was approved in the United States for the treatment of inhalational anthrax due to Bacillus anthracis in combination with appropriate antibacterial drugs, and for prophylaxis of inhalational anthrax when alternative therapies are not available or are not appropriate.[3][4]

Order information

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Catalog No.	Package	Price(In USD)	Qty (Quantity)	Sum(In USD)
GMP-Bios-INN-968-1mg	1mg	3090
GMP-Bios-INN-968-10mg	10mg	Inquiry
GMP-Bios-INN-968-100mg	100mg	Inquiry
GMP-Bios-INN-968-xmg	≥100mg	Inquiry
			Shipping Cost:	760.00
			Total:

Description

Products Name (INN Index)	Pre-Made Raxibacumab Biosimilar, Whole Mab: Anti-Anthrax Protective Antigen (Pa) [Bacillus Anthracis] therapeutic antibody
INN Name	Raxibacumab
Target	anthrax protective antigen (PA) [Bacillus anthracis]
Format	Whole mAb
Derivation	human
Species Reactivity	human
CH1 Isotype	IgG1 - lambda
VD LC	IgG1 - lambda
Highest_Clin_Trial (Jan '20)
Est. Status
100% SI Structure
99% SI Structure
95-98% SI Structure
Year Proposed
Year Recommended
Companies	GlaxoSmithKline (Brentford UK) / Human Genome Sciences Inc. (HGSI) (Rockville MD USA)
Conditions Approved
Conditions Active
Conditions Discontinued
Development Tech	Cambridge Antibody Technology (CAT) human antibody phage display library