Pre-made Muromonab-Cd3 benchmark antibody (Whole mAb, anti-CD3E therapeutic antibody, Anti-CD3epsilon/IMD18/T3E/TCRE Antibody) for drug discovery and mechanism of action (MOA) research

Anti-CD3E therapeutic antibody (Pre-made Muromonab-Cd3 biosimilar, Whole mAb) is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Muromonab-CD3 (trade name Orthoclone OKT3, marketed by Janssen-Cilag) is an immunosuppressant drug given to reduce acute rejection in patients with organ transplants.[1][2] It is a monoclonal antibody targeted at the CD3 receptor,[3] a membrane protein on the surface of T cells. It was the first monoclonal antibody to be approved for clinical use in humans.[2]

Order information

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Catalog No.	Package	Price(In USD)	Qty (Quantity)	Sum(In USD)
GMP-Bios-INN-921-1mg	1mg	3090
GMP-Bios-INN-921-10mg	10mg	Inquiry
GMP-Bios-INN-921-100mg	100mg	Inquiry
GMP-Bios-INN-921-xmg	≥100mg	Inquiry
			Shipping Cost:	760.00
			Total:

Description

Products Name (INN Index)	Pre-Made Muromonab-Cd3 3Iosimilar, Whole Mab, Anti-Cd3E Antibody: Anti-CD3epsilon/IMD18/T3E/TCRE therapeutic antibody
INN Name	Muromonab-Cd3
Target	CD3E
Format	Whole mAb
Derivation	Mus musculus
Species Reactivity	human
CH1 Isotype	IgG2a - kappa
VD LC	IgG2a - kappa
Highest_Clin_Trial (Jan '20)
Est. Status
100% SI Structure
99% SI Structure
95-98% SI Structure
Year Proposed
Year Recommended
Companies	Centocor Ortho Biotech Products LP (Raritan NJ USA) / Janssen Biotech, Inc (Horsham PA USA)
Conditions Approved
Conditions Active
Conditions Discontinued
Development Tech	0