Pre-made Mapatumumab benchmark antibody (Whole mAb, anti-TNFRSF10A/TRAIL-R1 therapeutic antibody, Anti-APO2/CD261/DR4/TRAILR-1/TRAILR1 Antibody) for drug discovery and mechanism of action (MOA) research

Anti-TNFRSF10A/TRAIL-R1 therapeutic antibody (Pre-made Mapatumumab biosimilar, Whole mAb) is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Mapatumumab (HGS-ETR1) is an experimental human monoclonal antibody undergoing clinical trials for the treatment of cancer.[1] It targets TRAIL-R1, also known as DR4, which is expressed on the surface of many tumor cell types.[2]

Order information

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Catalog No.	Package	Price(In USD)	Qty (Quantity)	Sum(In USD)
GMP-Bios-INN-905-1mg	1mg	3090
GMP-Bios-INN-905-10mg	10mg	Inquiry
GMP-Bios-INN-905-100mg	100mg	Inquiry
GMP-Bios-INN-905-xmg	≥100mg	Inquiry
			Shipping Cost:	760.00
			Total:

Description

Products Name (INN Index)	Pre-Made Mapatumumab Biosimilar, Whole Mab, Anti-TNFRSF10A/TRAIL-R1 Antibody: Anti-APO2/CD261/DR4/TRAILR-1/TRAILR1 therapeutic antibody
INN Name	Mapatumumab
Target	TNFRSF10A/TRAIL-R1
Format	Whole mAb
Derivation	human
Species Reactivity	human
CH1 Isotype	IgG1 - nd
VD LC	IgG1 - nd
Highest_Clin_Trial (Jan '20)
Est. Status
100% SI Structure
99% SI Structure
95-98% SI Structure
Year Proposed
Year Recommended
Companies	Cambridge Antibody Technology (Cambridge UK) / Human Genome Sciences Inc. (HGSI) (Rockville MD USA)
Conditions Approved
Conditions Active
Conditions Discontinued
Development Tech	Cambridge Antibody Technology (CAT) human antibody phage display library