Pre-made Indusatumab Vedotin benchmark antibody (Whole mAb ADC, anti-GUCY2C therapeutic antibody, Anti-DIAR6/GC-C/GUC2C/MECILIL/STAR Antibody) for drug discovery and mechanism of action (MOA) research
Cat No.: GMP-Bios-INN-866
Pre-made Indusatumab Vedotin benchmark antibody (Whole mAb ADC, anti-GUCY2C therapeutic antibody, Anti-DIAR6/GC-C/GUC2C/MECILIL/STAR Antibody) is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Indusatumab vedotin (MLN-264) is an antibody-drug conjugate that is under development for the treatment of pancreatic cancer[1] and other gastrointestinal cancers.[2] It consists of a monoclonal antibody (indusatumab) that targets the enzyme guanylate cyclase 2C which is present in some cancers, linked to an average of three to four molecules of the chemotherapeutic agent monomethyl auristatin E (MMAE).[3]
Order information
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Catalog No. | Package | Price(In USD) | Qty (Quantity) | Sum(In USD) |
---|---|---|---|---|
GMP-Bios-INN-866-1mg | 1mg | 4635 | ||
GMP-Bios-INN-866-10mg | 10mg | Inquiry | ||
GMP-Bios-INN-866-100mg | 100mg | Inquiry | ||
GMP-Bios-INN-866-xmg | ≥100mg | Inquiry | ||
Shipping Cost: | 760.00 | |||
Total: | ||||
Description
Products Name (INN Index) | Pre-Made Indusatumab Vedotin Biosimilar, Whole Mab Adc, Anti-Gucy2C Antibody: Anti-DIAR6/GC-C/GUC2C/MECILIL/STAR therapeutic antibody Drug Conjugate |
INN Name | Indusatumab Vedotin |
Target | GUCY2C |
Format | Whole mAb ADC |
Derivation | human |
Species Reactivity | human |
CH1 Isotype | IgG1 - kappa |
VD LC | IgG1 - kappa |
Highest_Clin_Trial (Jan '20) | |
Est. Status | |
100% SI Structure | |
99% SI Structure | |
95-98% SI Structure | |
Year Proposed | |
Year Recommended | |
Companies | Millennium Pharmaceuticals Inc. (Cambridge MA USA) |
Conditions Approved | |
Conditions Active | |
Conditions Discontinued | |
Development Tech | 0 |
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