Pre-made Glembatumumab Vedotin benchmark antibody (Whole mAb ADC, anti-GPNMB therapeutic antibody, Anti-HGFIN/NMB/PLCA3 Antibody) for drug discovery and mechanism of action (MOA) research
Cat No.: GMP-Bios-INN-856
Pre-made Glembatumumab Vedotin benchmark antibody (Whole mAb ADC, anti-GPNMB therapeutic antibody, Anti-HGFIN/NMB/PLCA3 Antibody) is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Glembatumumab vedotin (also known as CDX-11 and CR11-vcMMAE) is an antibody-drug conjugate (ADC) that targets cancer cells expressing transmembrane glycoprotein NMB (GPNMB).
Order information
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Catalog No. | Package | Price(In USD) | Qty (Quantity) | Sum(In USD) |
---|---|---|---|---|
GMP-Bios-INN-856-1mg | 1mg | 4635 | ||
GMP-Bios-INN-856-10mg | 10mg | Inquiry | ||
GMP-Bios-INN-856-100mg | 100mg | Inquiry | ||
GMP-Bios-INN-856-xmg | ≥100mg | Inquiry | ||
Shipping Cost: | 760.00 | |||
Total: | ||||
Description
Products Name (INN Index) | Pre-Made Glembatumumab Vedotin Biosimilar, Whole Mab Adc, Anti-Gpnmb Antibody: Anti-HGFIN/NMB/PLCA3 therapeutic antibody Drug Conjugate |
INN Name | Glembatumumab Vedotin |
Target | GPNMB |
Format | Whole mAb ADC |
Derivation | human |
Species Reactivity | human |
CH1 Isotype | IgG2 - kappa |
VD LC | IgG2 - kappa |
Highest_Clin_Trial (Jan '20) | |
Est. Status | |
100% SI Structure | |
99% SI Structure | |
95-98% SI Structure | |
Year Proposed | |
Year Recommended | |
Companies | Celldex Therapeutics, Inc. (Needham MA USA) |
Conditions Approved | |
Conditions Active | |
Conditions Discontinued | |
Development Tech | Abgenix's XenoMouse® |
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