Pre-made Gavilimomab benchmark antibody (Whole mAb, anti-BSG therapeutic antibody, Anti-5F7/CD147/EMMPRIN/EMPRIN/HAb18G/OK/TCSF Antibody) for drug discovery and mechanism of action (MOA) research
Cat No.: GMP-Bios-INN-853
Anti-BSG therapeutic antibody (Pre-made Gavilimomab biosimilar, Whole mAb) is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Gavilimomab (also known as ABX-CBL) is a mouse monoclonal antibody intended for use as an immunosuppressive biologic treatment of glucocorticoid-resistant graft versus host disease. It binds to the antigen CD147.[1] Gavilimomab proved slightly less effective than standard antithymocyte globulin therapy.[2]
Order information
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Catalog No. | Package | Price(In USD) | Qty (Quantity) | Sum(In USD) |
---|---|---|---|---|
GMP-Bios-INN-853-1mg | 1mg | 3090 | ||
GMP-Bios-INN-853-10mg | 10mg | Inquiry | ||
GMP-Bios-INN-853-100mg | 100mg | Inquiry | ||
GMP-Bios-INN-853-xmg | ≥100mg | Inquiry | ||
Shipping Cost: | 760.00 | |||
Total: | ||||
Description
Products Name (INN Index) | Pre-Made Gavilimomab Biosimilar, Whole Mab, Anti-Bsg Antibody: Anti-5F7/CD147/EMMPRIN/EMPRIN/HAb18G/OK/TCSF therapeutic antibody |
INN Name | Gavilimomab |
Target | BSG |
Format | Whole mAb |
Derivation | Mus musculus |
Species Reactivity | human |
CH1 Isotype | IgM - nd |
VD LC | IgM - nd |
Highest_Clin_Trial (Jan '20) | |
Est. Status | |
100% SI Structure | |
99% SI Structure | |
95-98% SI Structure | |
Year Proposed | |
Year Recommended | |
Companies | Abgenix (Fremont CA USA) |
Conditions Approved | |
Conditions Active | |
Conditions Discontinued | |
Development Tech | 0 |
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