Pre-Made Efmarodocokin Alfa Biosimilar, Fusion Protein targeting IL22RA1/IL22R1 fused with human IGHG4 Fc (Fragment constant): Recombinant therapeutic protein targeting CRF2-9 for drug discovery and mechanism of action (MOA) research
Cat No.: GMP-Bios-INN-821
Pre-Made Efmarodocokin Alfa Biosimilar, Fusion Protein targeting IL22RA1/IL22R1 fused with human IGHG4 Fc (Fragment constant): Recombinant therapeutic protein targeting CRF2-9 is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Interleukin-22 (IL-22) is produced by various leukocytes, it preferentially targets cells with epithelial origins. IL-22 exerts essential roles in modulating various tissue epithelial functions, such as innate host defense against extracellular pathogens, barrier integrity, regeneration, and wound healing. Therefore, IL-22 is thought to have therapeutic potential in treating diseases associated with infection, tissue injury or chronic tissue damage. Efmarodocokin Alfa is an IL-22 recombinant fusion protein that links the human cytokine IL-22 with the Fc portion of a human immunoglobulin.
Order information
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Catalog No. | Package | Price(In USD) | Qty (Quantity) | Sum(In USD) |
---|---|---|---|---|
GMP-Bios-INN-821-1mg | 1mg | 3090 | ||
GMP-Bios-INN-821-10mg | 10mg | Inquiry | ||
GMP-Bios-INN-821-100mg | 100mg | Inquiry | ||
GMP-Bios-INN-821-xmg | ≥100mg | Inquiry | ||
Shipping Cost: | 760.00 | |||
Total: | ||||
Description
Products Name (INN Index) | Pre-Made Efmarodocokin Alfa Biosimilar, Fusion Protein targeting IL22RA1/IL22R1 fused with human IGHG4 Fc (Fragment constant): Recombinant therapeutic protein targeting CRF2-9 |
INN Name | Efmarodocokin Alfa |
Target | IL22RA1 |
Format | Fusion Protein |
Derivation | human |
Species Reactivity | human |
CH1 Isotype | Fusion - IL22 (interleukin 22, IL-22, ILTIF, IL-TIF) - IGHG4 Fc (Fragment constant) |
VD LC | Fusion - IL22 (interleukin 22, IL-22, ILTIF, IL-TIF) - IGHG4 Fc (Fragment constant) |
Highest_Clin_Trial (Jan '20) | |
Est. Status | |
100% SI Structure | |
99% SI Structure | |
95-98% SI Structure | |
Year Proposed | |
Year Recommended | |
Companies | Genentech Inc. (S.San Francisco CA USA) Company |
Conditions Approved | |
Conditions Active | |
Conditions Discontinued | |
Development Tech | 0 |
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