Pre-made Efdamrofusp Alfa benchmark antibody (Bispecific, anti-C3/CO3;C4B;VEGFA therapeutic antibody, Anti-AHUS5/ARMD9/ASP/CPAMD1/HEL-S-62p;CH/C4F/CO4/C4BD/C4B12/CPAMD3;VPF/MVCD1 Antibody) for drug discovery and mechanism of action (MOA) research
Cat No.: GMP-Bios-INN-813
Pre-made Efdamrofusp Alfa benchmark antibody (Bispecific, anti-C3/CO3;C4B;VEGFA therapeutic antibody, Anti-AHUS5/ARMD9/ASP/CPAMD1/HEL-S-62p;CH/C4F/CO4/C4BD/C4B12/CPAMD3;VPF/MVCD1 Antibody) is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
VEGFR1/VEGFR2 fragments-IgG1 Fc-CR1 fusion protein: human
vascular endothelial growth factor receptor 1 (VEGFR1) (104-204)-
peptide (containing the Ig-like C2-type domain 2) (1-101) / human
vascular endothelial growth factor receptor 2 (VEGFR2) (206-308)-
peptide (containing the Ig-like C2-type domain 3) (102-204) / human
immunoglobulin G1 heavy chain constant region C-terminal 227-peptide
fragment (IgG1 Fc) (205-431) [human IGHG1*01; hinge: 205-
214; CH2: 215-324; CH3: 325-429; CHS: 430-431] / G6 peptide linker
(432-437) / human complement receptor type 1 (CR1) [N29>K466,
S37>Y474, G79>D516, D109>N546] (1-192)-peptide (438-629) fusion protein,
dimer (210-210':213-213')-bisdisulfide, produced in Chinese hamster
ovary (CHO) cells, glycoform alfa
angiogenesis inhibit
Order information
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Catalog No. | Package | Price(In USD) | Qty (Quantity) | Sum(In USD) |
---|---|---|---|---|
GMP-Bios-INN-813-1mg | 1mg | Inquiry | ||
GMP-Bios-INN-813-10mg | 10mg | Inquiry | ||
GMP-Bios-INN-813-100mg | 100mg | Inquiry | ||
GMP-Bios-INN-813-xmg | ≥100mg | Inquiry | ||
Shipping Cost: | 760.00 | |||
Total: | ||||
Description
Products Name (INN Index) | Pre-Made Efdamrofusp Alfa P Alfaiosimilar, Bispecific, Anti-C3/CO3;C4B;VEGFA Antibody: Anti-AHUS5/ARMD9/ASP/CPAMD1/HEL-S-62p;CH/C4F/CO4/C4BD/C4B12/CPAMD3;VPF/MVCD1 therapeutic antibody |
INN Name | Efdamrofusp Alfa |
Target | C3/CO3;C4B;VEGFA |
Format | Bispecific |
Derivation | |
Species Reactivity | |
CH1 Isotype | |
VD LC | |
Highest_Clin_Trial (Jan '20) | |
Est. Status | |
100% SI Structure | |
99% SI Structure | |
95-98% SI Structure | |
Year Proposed | |
Year Recommended | |
Companies | |
Conditions Approved | |
Conditions Active | |
Conditions Discontinued | |
Development Tech |
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