Pre-Made Detumomab biosimilar, Recombinant Protein: Recombinant therapeutic protein targeting human B-cell lymphoma for drug discovery and mechanism of action (MOA) research

Cat No.: GMP-Bios-INN-802

Pre-Made Detumomab biosimilar, Recombinant Protein: Recombinant therapeutic protein targeting human B-cell lymphoma is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Detumomab is a mouse monoclonal antibody targeting human B-cell lymphoma.[1][2]

Detumomab is comprised of an anti-B-cell lymphomas monoclonal antibody conjugated via a MC-Vc-PAB linker to SN38. The SN-38 is targeted to certain cancers by immunerecognition and delivered into cancer cells via receptor mediated endocytosis. Within the cell, SN-38 binds to DNA, causes DNA damage.

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Catalog No. Package Price(In USD) Qty (Quantity) Sum(In USD)
GMP-Bios-INN-802-1mg 1mg 3090
GMP-Bios-INN-802-10mg 10mg Inquiry
GMP-Bios-INN-802-100mg 100mg Inquiry
GMP-Bios-INN-802-xmg ≥100mg Inquiry
Shipping Cost: 760.00
Total:



Description

Products Name (INN Index) Pre-Made Detumomab biosimilar, Recombinant Protein: Recombinant therapeutic protein targeting human B-cell lymphoma
INN Name Detumomab
Targethuman B-cell lymphoma
FormatRecombinant Protein
DerivationMus musculus
Species Reactivityhuman
CH1 Isotype0
VD LC0
Highest_Clin_Trial (Jan '20)
Est. Status
100% SI Structure
99% SI Structure
95-98% SI Structure
Year Proposed
Year Recommended
CompaniesBiogen, Inc. (Cambridge MA USA)
Conditions Approved
Conditions Active
Conditions Discontinued
Development Tech0