Pre-Made Detumomab biosimilar, Recombinant Protein: Recombinant therapeutic protein targeting human B-cell lymphoma for drug discovery and mechanism of action (MOA) research
Cat No.: GMP-Bios-INN-802
Pre-Made Detumomab biosimilar, Recombinant Protein: Recombinant therapeutic protein targeting human B-cell lymphoma is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Detumomab is a mouse monoclonal antibody targeting human B-cell lymphoma.[1][2]
Detumomab is comprised of an anti-B-cell lymphomas monoclonal antibody conjugated via a MC-Vc-PAB linker to SN38. The SN-38 is targeted to certain cancers by immunerecognition and delivered into cancer cells via receptor mediated endocytosis. Within the cell, SN-38 binds to DNA, causes DNA damage.
Order information
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Catalog No. | Package | Price(In USD) | Qty (Quantity) | Sum(In USD) |
---|---|---|---|---|
GMP-Bios-INN-802-1mg | 1mg | 3090 | ||
GMP-Bios-INN-802-10mg | 10mg | Inquiry | ||
GMP-Bios-INN-802-100mg | 100mg | Inquiry | ||
GMP-Bios-INN-802-xmg | ≥100mg | Inquiry | ||
Shipping Cost: | 760.00 | |||
Total: | ||||
Description
Products Name (INN Index) | Pre-Made Detumomab biosimilar, Recombinant Protein: Recombinant therapeutic protein targeting human B-cell lymphoma |
INN Name | Detumomab |
Target | human B-cell lymphoma |
Format | Recombinant Protein |
Derivation | Mus musculus |
Species Reactivity | human |
CH1 Isotype | 0 |
VD LC | 0 |
Highest_Clin_Trial (Jan '20) | |
Est. Status | |
100% SI Structure | |
99% SI Structure | |
95-98% SI Structure | |
Year Proposed | |
Year Recommended | |
Companies | Biogen, Inc. (Cambridge MA USA) |
Conditions Approved | |
Conditions Active | |
Conditions Discontinued | |
Development Tech | 0 |
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