Pre-made Cantuzumab Mertansine benchmark antibody (Whole mAb ADC, anti-MUC1 therapeutic antibody, Anti-ADMCKD/ADMCKD1/ADTKD2/CA 15-3/CD227/Ca15-3/EMA/H23AG/KL-6/MAM6/MCD/MCKD/MCKD1/SEC/X/ZD/PEM/PEMT/PUM Antibody) for drug discovery and mechanism of action (MOA) research
Cat No.: GMP-Bios-INN-769
Pre-made Cantuzumab Mertansine benchmark antibody (Whole mAb ADC, anti-MUC1 therapeutic antibody, Anti-ADMCKD/ADMCKD1/ADTKD2/CA 15-3/CD227/Ca15-3/EMA/H23AG/KL-6/MAM6/MCD/MCKD/MCKD1/SEC/X/ZD/PEM/PEMT/PUM Antibody) is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Cantuzumab mertansine (SB-4875; huC242-DM1) is an antibody-drug conjugate investigated to treat colorectal cancer and other types of cancer.[1] It is a humanized monoclonal antibody, cantuzumab (huC242) linked to a cytotoxic agent, mertansine (DM1).[2] It was developed by ImmunoGen.
Order information
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Catalog No. | Package | Price(In USD) | Qty (Quantity) | Sum(In USD) |
---|---|---|---|---|
GMP-Bios-INN-769-1mg | 1mg | Inquiry | ||
GMP-Bios-INN-769-10mg | 10mg | Inquiry | ||
GMP-Bios-INN-769-100mg | 100mg | Inquiry | ||
GMP-Bios-INN-769-xmg | ≥100mg | Inquiry | ||
Shipping Cost: | 760.00 | |||
Total: | ||||
Description
Products Name (INN Index) | Pre-Made Cantuzumab Mertansine Biosimilar, Whole Mab Adc, Anti-Muc1 Antibody: Anti-ADMCKD/ADMCKD1/ADTKD2/CA 15-3/CD227/Ca15-3/EMA/H23AG/KL-6/MAM6/MCD/MCKD/MCKD1/SEC/X/ZD/PEM/PEMT/PUM therapeutic antibody Drug Conjugate |
INN Name | Cantuzumab Mertansine |
Target | MUC1 |
Format | Whole mAb ADC |
Derivation | Humanized |
Species Reactivity | human |
CH1 Isotype | IgG1 - kappa |
VD LC | IgG1 - kappa |
Highest_Clin_Trial (Jan '20) | |
Est. Status | |
100% SI Structure | |
99% SI Structure | |
95-98% SI Structure | |
Year Proposed | |
Year Recommended | |
Companies | GlaxoSmithKline (Brentford UK) / ImmunoGen Inc. (Cambridge MA USA) |
Conditions Approved | |
Conditions Active | |
Conditions Discontinued | |
Development Tech | 0 |
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