Pre-made Biciromab benchmark antibody (Radiolabelled antibody, anti-fibrin II therapeutic antibody) for drug discovery and mechanism of action (MOA) research
Cat No.: GMP-Bios-INN-759
Pre-made Biciromab benchmark antibody (Radiolabelled antibody, anti-fibrin II therapeutic antibody) is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Indium (111In) biciromab (INN, trade name FibriScint, developed by Centocor) was a drug targeting fibrin, a protein involved in the clotting of blood.[1] It was the Fab' fragment of a mouse monoclonal antibody labelled with the radioisotope indium-111 for the diagnosis of thromboembolism,[2] but was withdrawn during clinical trials.[3]
Order information
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| Catalog No. | Package | Price(In USD) | Qty (Quantity) | Sum(In USD) |
|---|---|---|---|---|
| GMP-Bios-INN-759-1mg | 1mg | 3090 | ||
| GMP-Bios-INN-759-10mg | 10mg | Inquiry | ||
| GMP-Bios-INN-759-100mg | 100mg | Inquiry | ||
| GMP-Bios-INN-759-xmg | ≥100mg | Inquiry | ||
| Shipping Cost: | 760.00 | |||
| Total: | ||||
Description
| Products Name (INN Index) | Pre-Made Biciromab Biosimilar, Radiolabelled Antibody: Anti-Fibrin Ii therapeutic antibody |
| INN Name | Biciromab |
| Target | fibrin II |
| Format | Radiolabelled antibody |
| Derivation | Mus musculus |
| Species Reactivity | human |
| CH1 Isotype | Fab' - G1 - kappa |
| VD LC | Fab' - G1 - kappa |
| Highest_Clin_Trial (Jan '20) | |
| Est. Status | |
| 100% SI Structure | |
| 99% SI Structure | |
| 95-98% SI Structure | |
| Year Proposed | |
| Year Recommended | |
| Companies | Centocor Inc. (Horsham PA USA) |
| Conditions Approved | |
| Conditions Active | |
| Conditions Discontinued | |
| Development Tech | 0 |

