Pre-made Biciromab benchmark antibody (Radiolabelled antibody, anti-fibrin II therapeutic antibody) for drug discovery and mechanism of action (MOA) research

Pre-made Biciromab benchmark antibody (Radiolabelled antibody, anti-fibrin II therapeutic antibody) is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Indium (111In) biciromab (INN, trade name FibriScint, developed by Centocor) was a drug targeting fibrin, a protein involved in the clotting of blood.[1] It was the Fab' fragment of a mouse monoclonal antibody labelled with the radioisotope indium-111 for the diagnosis of thromboembolism,[2] but was withdrawn during clinical trials.[3]

Order information

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Catalog No.	Package	Price(In USD)	Qty (Quantity)	Sum(In USD)
GMP-Bios-INN-759-1mg	1mg	3090
GMP-Bios-INN-759-10mg	10mg	Inquiry
GMP-Bios-INN-759-100mg	100mg	Inquiry
GMP-Bios-INN-759-xmg	≥100mg	Inquiry
			Shipping Cost:	760.00
			Total:

Description

Products Name (INN Index)	Pre-Made Biciromab Biosimilar, Radiolabelled Antibody: Anti-Fibrin Ii therapeutic antibody
INN Name	Biciromab
Target	fibrin II
Format	Radiolabelled antibody
Derivation	Mus musculus
Species Reactivity	human
CH1 Isotype	Fab' - G1 - kappa
VD LC	Fab' - G1 - kappa
Highest_Clin_Trial (Jan '20)
Est. Status
100% SI Structure
99% SI Structure
95-98% SI Structure
Year Proposed
Year Recommended
Companies	Centocor Inc. (Horsham PA USA)
Conditions Approved
Conditions Active
Conditions Discontinued
Development Tech	0