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Pre-Made Batiraxcept Biosimilar, Fusion Protein targeting GAS6 fused with human IGHG1 Fc (Fragment constant): Recombinant therapeutic protein targeting AXLLG/AXSF for drug discovery and mechanism of action (MOA) research
Cat No.: GMP-Bios-INN-750
Pre-Made Batiraxcept Biosimilar, Fusion Protein targeting GAS6 fused with human IGHG1 Fc (Fragment constant): Recombinant therapeutic protein targeting AXLLG/AXSF is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Batiraxcept is a soluble fusion protein comprised of the extracellular domain of the receptor tyrosine kinase (RTK) AXL (UFO) fused to a human immunoglobulin G1 (IgG1) Fc domain, with potential antineoplastic activity. Batiraxcept selectively binds to growth arrest-specific protein 6 (GAS6), the endogenous ligand for AXL. This may inhibit GAS6/AXL-mediated signaling, which plays a key role in tumor cell proliferation, survival, invasion and metastasis, as well as immune evasion and resistance to other anticancer agents.
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| Catalog No. | Package | Price(In USD) | Qty (Quantity) | Sum(In USD) |
|---|---|---|---|---|
| GMP-Bios-INN-750-1mg | 1mg | 3090 | ||
| GMP-Bios-INN-750-10mg | 10mg | Inquiry | ||
| GMP-Bios-INN-750-100mg | 100mg | Inquiry | ||
| GMP-Bios-INN-750-xmg | ≥100mg | Inquiry | ||
| Shipping Cost: | 760.00 | |||
| Total: | ||||
Description
| Products Name (INN Index) | Pre-Made Batiraxcept Biosimilar, Fusion Protein targeting GAS6 fused with human IGHG1 Fc (Fragment constant): Recombinant therapeutic protein targeting AXLLG/AXSF |
| INN Name | Batiraxcept |
| Target | GAS6 |
| Format | Fusion Protein |
| Derivation | human |
| Species Reactivity | human |
| CH1 Isotype | Fusion - [AXL (AXL receptor tyrosine kinase, ARK, JTK11, Tyro7, UFO)]2 - IGHG1 Fc (Fragment constant) |
| VD LC | Fusion - [AXL (AXL receptor tyrosine kinase, ARK, JTK11, Tyro7, UFO)]2 - IGHG1 Fc (Fragment constant) |
| Highest_Clin_Trial (Jan '20) | |
| Est. Status | |
| 100% SI Structure | |
| 99% SI Structure | |
| 95-98% SI Structure | |
| Year Proposed | |
| Year Recommended | |
| Companies | Aravive Biologics, Inc. (Houston TX USA) |
| Conditions Approved | |
| Conditions Active | |
| Conditions Discontinued | |
| Development Tech | 0 |
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