Pre-Made Balugrastim Biosimilar, Fusion Protein targeting CSF3R/G-CSF-R fused with ALB (albumin, human serum albumin, HSA): Recombinant therapeutic protein targeting CD114/GCSFR/SCN7 for drug discovery and mechanism of action (MOA) research

Cat No.: GMP-Bios-INN-748

Pre-Made Balugrastim Biosimilar, Fusion Protein targeting CSF3R/G-CSF-R fused with ALB (albumin, human serum albumin, HSA): Recombinant therapeutic protein targeting CD114/GCSFR/SCN7 is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Balugrastim has been used in trials studying the treatment of Solid Tumors. Neutropenia is one of the most common toxicities in cancer patients receiving myelosuppressive chemotherapy. Patients who develop neutropenia are at increased risk for infection with fever. Balugrastim is a recombinant granulocyte colony-stimulating factors (G-CSFs) reduce the incidence and duration of chemotherapy-induced neutropenia and febrile neutropenia when given as adjunct therapy to patients receiving myelosuppressive chemotherapy. Balugrastim is a long-acting G-CSF composed of a genetic fusion between recombinant human serum albumin and G-CSF.

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Catalog No. Package Price(In USD) Qty (Quantity) Sum(In USD)
GMP-Bios-INN-748-1mg 1mg 3090
GMP-Bios-INN-748-10mg 10mg Inquiry
GMP-Bios-INN-748-100mg 100mg Inquiry
GMP-Bios-INN-748-xmg ≥100mg Inquiry
Shipping Cost: 760.00
Total:



Description

Products Name (INN Index) Pre-Made Balugrastim Biosimilar, Fusion Protein targeting CSF3R/G-CSF-R fused with ALB (albumin, human serum albumin, HSA): Recombinant therapeutic protein targeting CD114/GCSFR/SCN7
INN Name Balugrastim
TargetCSF3R/G-CSF-R
FormatFusion Protein
Derivationhuman
Species Reactivityhuman
CH1 IsotypeFusion - ALB (albumin, human serum albumin, HSA) 25-609 - CSF3 (colony stimulating factor 3, GCSF, granulocyte colony-stimulating factor, G-CSF)
VD LCFusion - ALB (albumin, human serum albumin, HSA) 25-609 - CSF3 (colony stimulating factor 3, GCSF, granulocyte colony-stimulating factor, G-CSF)
Highest_Clin_Trial (Jan '20)
Est. Status
100% SI Structure
99% SI Structure
95-98% SI Structure
Year Proposed
Year Recommended
CompaniesGlaxoSmithKline (Brentford UK) / Teva Pharmaceutical Industries Ltd (Cephalon) (Frazer PA USA)
Conditions Approved
Conditions Active
Conditions Discontinued
Development Tech0