Pre-made Afelimomab benchmark antibody (Fab Fusion, anti-TNF therapeutic antibody, Anti-DIF/TNFSF2/TNLG1F Antibody) for drug discovery and mechanism of action (MOA) research

Cat No.: GMP-Bios-INN-721

Pre-made Afelimomab benchmark antibody (Fab Fusion, anti-TNF therapeutic antibody, Anti-DIF/TNFSF2/TNLG1F Antibody) is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Afelimomab (MAK 195F) is an anti-TNFα monoclonal antibody. Administration of afelimomab reduces the concentration of interleukin-6 in patients with sepsis, but reduces mortality only marginally.[1][2]

Order information


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Catalog No. Package Price(In USD) Qty (Quantity) Sum(In USD)
GMP-Bios-INN-721-1mg 1mg 3090
GMP-Bios-INN-721-10mg 10mg Inquiry
GMP-Bios-INN-721-100mg 100mg Inquiry
GMP-Bios-INN-721-xmg ≥100mg Inquiry
Shipping Cost: 760.00
Total:



Description

Products Name (INN Index) Pre-Made Afelimomab Biosimilar, Fab Fusion, Anti-Tnf Antibody: Anti-DIF/TNFSF2/TNLG1F therapeutic antibody
INN Name Afelimomab
TargetTNF
FormatFab Fusion
DerivationMus musculus
Species Reactivityhuman
CH1 IsotypeF(ab')2 - G3 - kappa
VD LCF(ab')2 - G3 - kappa
Highest_Clin_Trial (Jan '20)
Est. Status
100% SI Structure
99% SI Structure
95-98% SI Structure
Year Proposed
Year Recommended
CompaniesAbbott Laboratories (Abbott Park IL USA) / Knoll Pharmaceutical (Mount Olive NJ USA)
Conditions Approved
Conditions Active
Conditions Discontinued
Development Tech0